ATRN

This gene encodes both membrane-bound and secreted protein isoforms. A membrane-bound isoform exhibits sequence similarity with the mouse mahogany protein, a receptor involved in controlling obesity. A secreted isoform is involved in the initial immune cell clustering during inflammatory responses that may regulate the chemotactic activity of chemokines.
Full Name
ATTRACTIN
Function
Involved in the initial immune cell clustering during inflammatory response and may regulate chemotactic activity of chemokines. May play a role in melanocortin signaling pathways that regulate energy homeostasis and hair color. Low-affinity receptor for agouti (By similarity).
Has a critical role in normal myelination in the central nervous system (By similarity).
Biological Process
Animal organ morphogenesis Source: GO_Central
Cell migration Source: GO_Central
Cerebellum development Source: Ensembl
Inflammatory response Source: UniProtKB-KW
Myelination Source: Ensembl
Pigmentation Source: Ensembl
Regulation of multicellular organism growth Source: Ensembl
Response to oxidative stress Source: Ensembl
Substrate adhesion-dependent cell spreading Source: GO_Central
Tissue development Source: GO_Central
Cellular Location
Isoform 1: Cell membrane
Isoform 2: Secreted
Isoform 3: Secreted
Topology
Extracellular: 84-1279 aa
Helical: 1280-1300 aa
Cytoplasmic: 1301-1429 aa
PTM
Heavily glycosylated.
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Anti-ATRN antibodies

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Mouse Anti-ATRN Recombinant Antibody (CBFYM-0876) (CBMAB-M1023-FY)

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Target: ATRN
Host: Mouse
Antibody Isotype: IgM, κ
Specificity: Mouse, Rat, Human
Clone: CBFYM-0876
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-ATRN Recombinant Antibody (CBYC-A896) (CBMAB-A4147-YC)

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Target: ATRN
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: CBYC-A896
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-ATRN Recombinant Antibody (D-8) (CBMAB-A4145-YC)

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Target: ATRN
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat
Clone: D-8
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-ATRN Recombinant Antibody (9H8) (CBMAB-A4144-YC)

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Target: ATRN
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 9H8
Application*: WB, IP
Datasheet SDS
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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