CADM4
CADM4 (Cell Adhesion Molecule 4) is a Protein Coding gene. Diseases associated with CADM4 include Renal Clear Cell Carcinoma and Cleft Lip/Palate-Ectodermal Dysplasia Syndrome. An important paralog of this gene is CADM1.
Full Name
Cell Adhesion Molecule 4
Function
Involved in the cell-cell adhesion. Has calcium- and magnesium-independent cell-cell adhesion activity. May have tumor-suppressor activity.
Biological Process
Cell adhesion Source: UniProtKB-KW
Negative regulation of peptidyl-threonine phosphorylation Source: UniProtKB
Negative regulation of peptidyl-tyrosine phosphorylation Source: UniProtKB
Negative regulation of protein phosphorylation Source: UniProtKB
Negative regulation of vascular endothelial growth factor receptor signaling pathway Source: UniProtKB
Negative regulation of vascular endothelial growth factor signaling pathway Source: UniProtKB
Regulation of cell motility Source: UniProtKB
Regulation of cell population proliferation Source: UniProtKB
Regulation of protein phosphorylation Source: UniProtKB
Regulation of Rac protein signal transduction Source: UniProtKB
Regulation of wound healing Source: UniProtKB
Negative regulation of peptidyl-threonine phosphorylation Source: UniProtKB
Negative regulation of peptidyl-tyrosine phosphorylation Source: UniProtKB
Negative regulation of protein phosphorylation Source: UniProtKB
Negative regulation of vascular endothelial growth factor receptor signaling pathway Source: UniProtKB
Negative regulation of vascular endothelial growth factor signaling pathway Source: UniProtKB
Regulation of cell motility Source: UniProtKB
Regulation of cell population proliferation Source: UniProtKB
Regulation of protein phosphorylation Source: UniProtKB
Regulation of Rac protein signal transduction Source: UniProtKB
Regulation of wound healing Source: UniProtKB
Cellular Location
Membrane
Topology
Extracellular: 21-324 aa
Helical: 325-345 aa
Cytoplasmic: 346-388 aa
Helical: 325-345 aa
Cytoplasmic: 346-388 aa
PTM
N-glycosylated.
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Anti-CADM4 antibodies
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CompareTarget: CADM4
Host: Rat
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: CBYY-I1277
Application*: WB
Target: CADM4
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat
Clone: CBYY-I0813
Application*: WB, IH, IF
Target: CADM4
Host: Rat
Antibody Isotype: IgG1
Specificity: Human
Clone: 404619
Application*: FC, IC, IF, WB
Target: CADM4
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-324
Tag: His Tag
Target: CADM4
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-323
Tag: hFc Tag
Target: CADM4
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-323
Tag: His Tag
Target: CADM4
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: EG460
Application*: WB
Target: CADM4
Host: Rat
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C0868
Application*: IH
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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