CADM4

CADM4 (Cell Adhesion Molecule 4) is a Protein Coding gene. Diseases associated with CADM4 include Renal Clear Cell Carcinoma and Cleft Lip/Palate-Ectodermal Dysplasia Syndrome. An important paralog of this gene is CADM1.

Cell Adhesion Molecule 4

Involved in the cell-cell adhesion. Has calcium- and magnesium-independent cell-cell adhesion activity. May have tumor-suppressor activity.

Cell adhesion Source: UniProtKB-KW
Negative regulation of peptidyl-threonine phosphorylation Source: UniProtKB
Negative regulation of peptidyl-tyrosine phosphorylation Source: UniProtKB
Negative regulation of protein phosphorylation Source: UniProtKB
Negative regulation of vascular endothelial growth factor receptor signaling pathway Source: UniProtKB
Negative regulation of vascular endothelial growth factor signaling pathway Source: UniProtKB
Regulation of cell motility Source: UniProtKB
Regulation of cell population proliferation Source: UniProtKB
Regulation of protein phosphorylation Source: UniProtKB
Regulation of Rac protein signal transduction Source: UniProtKB
Regulation of wound healing Source: UniProtKB

Membrane

Extracellular: 21-324 aa
Helical: 325-345 aa
Cytoplasmic: 346-388 aa

N-glycosylated.