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CCL22

CCL22 (C-C Motif Chemokine Ligand 22) is a Protein Coding gene. Diseases associated with CCL22 include Eosinophilic Pneumonia and Dermatitis. Among its related pathways are PEDF Induced Signaling and Cytokine Signaling in Immune system. Gene Ontology (GO) annotations related to this gene include chemokine activity.
Full Name
C-C Motif Chemokine Ligand 22
Function
May play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. Chemotactic for monocytes, dendritic cells and natural killer cells. Mild chemoattractant for primary activated T-lymphocytes and a potent chemoattractant for chronically activated T-lymphocytes but has no chemoattractant activity for neutrophils, eosinophils, and resting T-lymphocytes. Binds to CCR4. Processed forms MDC(3-69), MDC(5-69) and MDC(7-69) seem not be active.
Biological Process
Antimicrobial humoral immune response mediated by antimicrobial peptide Source: UniProtKB
Cell-cell signaling Source: ProtInc
Cellular response to interferon-gamma Source: GO_Central
Cellular response to interleukin-1 Source: GO_Central
Cellular response to tumor necrosis factor Source: GO_Central
Chemokine-mediated signaling pathway Source: GO_Central
Chemotaxis Source: ProtInc
Cytokine-mediated signaling pathway Source: Reactome
G protein-coupled receptor signaling pathway Source: GO_Central
Immune response Source: ProtInc
Inflammatory response Source: GO_Central
Killing of cells of other organism Source: UniProtKB
Lymphocyte chemotaxis Source: GO_Central
Monocyte chemotaxis Source: GO_Central
Neutrophil chemotaxis Source: GO_Central
Positive regulation of ERK1 and ERK2 cascade Source: GO_Central
Positive regulation of GTPase activity Source: GO_Central
Response to virus Source: ProtInc
Signal transduction Source: ProtInc
Cellular Location
Secreted
PTM
The N-terminal processed forms MDC(3-69), MDC(5-69) and MDC(7-69) are produced by proteolytic cleavage after secretion from monocyte derived dendrocytes.
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Anti-CCL22 antibodies

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Rat Anti-CCL22 Recombinant Antibody (158113) (CBMAB-C3224-LY)

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Target: CCL22
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: 158113
Application*: WB
Datasheet SDS

Mouse Anti-CCL22 Recombinant Antibody (CBXC-1253) (CBMAB-C1520-CQ)

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Target: CCL22
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXC-1253
Application*: E
Datasheet SDS

Rat Anti-CCL22 Recombinant Antibody (CBFYM-0930) (CBMAB-M1079-FY)

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Target: CCL22
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: CBFYM-0930
Application*: N, WB
Functional Assay
Datasheet SDS

Rat Anti-CCL22 Recombinant Antibody (CBFYM-0929) (CBMAB-M1078-FY)

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Target: CCL22
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: CBFYM-0929
Application*: N, WB
Functional Assay
Datasheet SDS

Mouse Anti-CCL22 Recombinant Antibody (CBFYM-0928) (CBMAB-M1077-FY)

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Target: CCL22
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYM-0928
Application*: E, WB
Datasheet SDS

Mouse Anti-CCL22 Recombinant Antibody (CBFYM-0927) (CBMAB-M1076-FY)

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Target: CCL22
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYM-0927
Application*: E
Datasheet SDS

Mouse Anti-CCL22 Recombinant Antibody (CBFYM-0926) (CBMAB-M1075-FY)

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Target: CCL22
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYM-0926
Application*: E
Datasheet SDS

Mouse Anti-CCL22 Recombinant Antibody (CBFYM-0925) (CBMAB-M1074-FY)

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Target: CCL22
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBFYM-0925
Application*: E, WB
Datasheet SDS
More Infomation
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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