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CCL22

CCL22 (C-C Motif Chemokine Ligand 22) is a Protein Coding gene. Diseases associated with CCL22 include Eosinophilic Pneumonia and Dermatitis. Among its related pathways are PEDF Induced Signaling and Cytokine Signaling in Immune system. Gene Ontology (GO) annotations related to this gene include chemokine activity.

Full Name

C-C Motif Chemokine Ligand 22

Function

May play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. Chemotactic for monocytes, dendritic cells and natural killer cells. Mild chemoattractant for primary activated T-lymphocytes and a potent chemoattractant for chronically activated T-lymphocytes but has no chemoattractant activity for neutrophils, eosinophils, and resting T-lymphocytes. Binds to CCR4. Processed forms MDC(3-69), MDC(5-69) and MDC(7-69) seem not be active.

Biological Process

Antimicrobial humoral immune response mediated by antimicrobial peptide Source: UniProtKB
Cell-cell signaling Source: ProtInc
Cellular response to interferon-gamma Source: GO_Central
Cellular response to interleukin-1 Source: GO_Central
Cellular response to tumor necrosis factor Source: GO_Central
Chemokine-mediated signaling pathway Source: GO_Central
Chemotaxis Source: ProtInc
Cytokine-mediated signaling pathway Source: Reactome
G protein-coupled receptor signaling pathway Source: GO_Central
Immune response Source: ProtInc
Inflammatory response Source: GO_Central
Killing of cells of other organism Source: UniProtKB
Lymphocyte chemotaxis Source: GO_Central
Monocyte chemotaxis Source: GO_Central
Neutrophil chemotaxis Source: GO_Central
Positive regulation of ERK1 and ERK2 cascade Source: GO_Central
Positive regulation of GTPase activity Source: GO_Central
Response to virus Source: ProtInc
Signal transduction Source: ProtInc

Cellular Location

Secreted

PTM

The N-terminal processed forms MDC(3-69), MDC(5-69) and MDC(7-69) are produced by proteolytic cleavage after secretion from monocyte derived dendrocytes.

Anti-CCL22 antibodies

Mouse Anti-CCL22 Recombinant Antibody (CBXC-0117) (CBMAB-C3638-CQ)

SDS

Target: CCL22

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBXC-0117

Application*: E, WB

Rat Anti-CCL22 Recombinant Antibody (CBXC-1452) (CBMAB-C3240-CQ)

SDS

Target: CCL22

Host: Rat

Antibody Isotype: IgG2

Specificity: Mouse

Clone: CBXC-1452

Application*: N, WB

Mouse Anti-CCL22 Recombinant Antibody (CBXC-0118) (CBMAB-C3230-CQ)

SDS

Target: CCL22

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBXC-0118

Application*: E

Mouse Anti-CCL22 Recombinant Antibody (CBXC-1253) (CBMAB-C1520-CQ)

SDS

Target: CCL22

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBXC-1253

Application*: IS

Rat Anti-CCL22 (AA 25-92) Recombinant Antibody (CBFYC-0962) (CBMAB-C1018-FY)

SDS

Target: CCL22

Host: Rat

Antibody Isotype: IgG2a

Specificity: Mouse

Clone: CBFYC-0962

Application*: N, EC

Rat Anti-CCL22 (AA 25-92) Recombinant Antibody (CBFYC-0961) (CBMAB-C1017-FY)

SDS

Target: CCL22

Host: Rat

Antibody Isotype: IgG2a

Specificity: Mouse

Clone: CBFYC-0961

Application*: WB

Rat Anti-CCL22 Recombinant Antibody (CBFYC-0960) (CBMAB-C1016-FY)

SDS

Target: CCL22

Host: Rat

Antibody Isotype: IgG2

Specificity: Mouse

Clone: CBFYC-0960

Application*: WB, N

Rat Anti-CCL22 Recombinant Antibody (158113) (CBMAB-C3224-LY)

SDS

Target: CCL22

Host: Rat

Antibody Isotype: IgG2a

Specificity: Mouse

Clone: 158113

Application*: WB

Rat Anti-CCL22 (AA 25-92) Recombinant Antibody (CBFYM-0932) (CBMAB-M1081-FY)

SDS

Target: CCL22

Host: Rat

Antibody Isotype: IgG2a

Specificity: Mouse

Clone: CBFYM-0932

Application*: ED, N

Rat Anti-CCL22 Recombinant Antibody (CBFYM-0930) (CBMAB-M1079-FY)

SDS

Target: CCL22

Host: Rat

Antibody Isotype: IgG2

Specificity: Mouse

Clone: CBFYM-0930

Application*: N, WB

Rat Anti-CCL22 Recombinant Antibody (CBFYM-0929) (CBMAB-M1078-FY)

SDS

Target: CCL22

Host: Rat

Specificity: Mouse

Clone: CBFYM-0929

Application*: WB, E

Mouse Anti-CCL22 Recombinant Antibody (CBFYM-0928) (CBMAB-M1077-FY)

SDS

Target: CCL22

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBFYM-0928

Application*: ED, N, WB

Mouse Anti-CCL22 Recombinant Antibody (CBFYM-0927) (CBMAB-M1076-FY)

SDS

Target: CCL22

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBFYM-0927

Application*: WB, SE

Mouse Anti-CCL22 Recombinant Antibody (CBFYM-0926) (CBMAB-M1075-FY)

SDS

Target: CCL22

Host: Mouse

Antibody Isotype: IgG2

Specificity: Human

Clone: CBFYM-0926

Application*: N, WB

Mouse Anti-CCL22 Recombinant Antibody (CBFYM-0925) (CBMAB-M1074-FY)

SDS

Target: CCL22

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBFYM-0925

Application*: E, FN, WB

Mouse Anti-CCL22 Recombinant Antibody (A028) (CBMAB-AP4440LY)

SDS

Target: CCL22

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: A028

Application*: Sandwich ELISA, Western Blot

Mouse Anti-CCL22 Recombinant Antibody (A027) (CBMAB-AP4349LY)

SDS

Target: CCL22

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: A027

Application*: ICC, IHC, IP, WB

Rat Anti-CCL22 Recombinant Antibody (RM0175-9L23) (CBMAB-C9832-LY)

SDS

Target: CCL22

Host: Rat

Antibody Isotype: IgG2

Specificity: Mouse

Clone: RM0175-9L23

Application*: WB, B/N

Mouse Anti-CCL22 Recombinant Antibody (MM0147-13G44) (CBMAB-C9831-LY)

SDS

Target: CCL22

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: MM0147-13G44

Application*: WB, B/N

Mouse Anti-CCL22 Recombinant Antibody (T51-719) (CBMAB-C9828-LY)

SDS

Target: CCL22

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: T51-719

Application*: F

Mouse Anti-CCL22 Recombinant Antibody (14L103) (CBMAB-C1412-CN)

SDS

Target: CCL22

Host: Mouse

Antibody Isotype: IgG2

Specificity: Human

Clone: 14L103

Application*: N, WB

Rat Anti-CCL22 Recombinant Antibody (CBYY-C1078) (CBMAB-C2515-YY)

SDS

Target: CCL22

Host: Rat

Antibody Isotype: IgG

Specificity: Human

Clone: CBYY-C1078

Application*: E, WB

Mouse Anti-CCL22 Recombinant Antibody (57226) (CBMAB-C1109-YY)

SDS

Target: CCL22

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: 57226

Application*: WB, N, E(Cap)

Mouse Anti-CCL22 Recombinant Antibody (57203) (CBMAB-C7220-LY)

SDS

Target: CCL22

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: 57203

Application*: WB, IS, MC

Mouse Anti-CCL22 Recombinant Antibody (4B5) (CBMAB-C6665-LY)

SDS

Target: CCL22

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 4B5

Application*: E

Rat Anti-CCL22 Recombinant Antibody (349/6) (CBMAB-C5547-LY)

SDS

Target: CCL22

Host: Rat

Antibody Isotype: IgG

Specificity: Human

Clone: 349/6

Application*: E, WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)

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