CCL24
CCL24 (C-C Motif Chemokine Ligand 24) is a Protein Coding gene. Diseases associated with CCL24 include Allergic Asthma and Allergic Hypersensitivity Disease. Among its related pathways are PEDF Induced Signaling and Akt Signaling. Gene Ontology (GO) annotations related to this gene include cytokine activity and chemokine activity. An important paralog of this gene is CCL13.
Full Name
C-C Motif Chemokine Ligand 24
Function
Chemotactic for resting T-lymphocytes, and eosinophils (PubMed:9104803, PubMed:9365122).
Has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes (PubMed:9104803, PubMed:9365122).
Is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line (PubMed:9104803, PubMed:9365122).
Binds to CCR3 (PubMed:9104803, PubMed:9365122).
Has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes (PubMed:9104803, PubMed:9365122).
Is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line (PubMed:9104803, PubMed:9365122).
Binds to CCR3 (PubMed:9104803, PubMed:9365122).
Biological Process
Cell-cell signaling Source: ProtInc
Cellular response to interferon-gamma Source: GO_Central
Cellular response to interleukin-1 Source: GO_Central
Cellular response to tumor necrosis factor Source: GO_Central
Chemokine-mediated signaling pathway Source: GO_Central
Chemotaxis Source: ProtInc
Cytoskeleton organization Source: UniProtKB
Eosinophil chemotaxis Source: UniProtKB
G protein-coupled receptor signaling pathway Source: GO_Central
Immune response Source: ProtInc
Inflammatory response Source: GO_Central
Lymphocyte chemotaxis Source: GO_Central
Monocyte chemotaxis Source: GO_Central
Neutrophil chemotaxis Source: GO_Central
Positive regulation of actin filament polymerization Source: BHF-UCL
Positive regulation of angiogenesis Source: Ensembl
Positive regulation of cell migration Source: BHF-UCL
Positive regulation of endothelial cell proliferation Source: BHF-UCL
Positive regulation of eosinophil migration Source: Ensembl
Positive regulation of ERK1 and ERK2 cascade Source: GO_Central
Positive regulation of GTPase activity Source: BHF-UCL
Positive regulation of inflammatory response Source: Ensembl
Regulation of cell shape Source: UniProtKB
Signal transduction Source: ProtInc
Cellular response to interferon-gamma Source: GO_Central
Cellular response to interleukin-1 Source: GO_Central
Cellular response to tumor necrosis factor Source: GO_Central
Chemokine-mediated signaling pathway Source: GO_Central
Chemotaxis Source: ProtInc
Cytoskeleton organization Source: UniProtKB
Eosinophil chemotaxis Source: UniProtKB
G protein-coupled receptor signaling pathway Source: GO_Central
Immune response Source: ProtInc
Inflammatory response Source: GO_Central
Lymphocyte chemotaxis Source: GO_Central
Monocyte chemotaxis Source: GO_Central
Neutrophil chemotaxis Source: GO_Central
Positive regulation of actin filament polymerization Source: BHF-UCL
Positive regulation of angiogenesis Source: Ensembl
Positive regulation of cell migration Source: BHF-UCL
Positive regulation of endothelial cell proliferation Source: BHF-UCL
Positive regulation of eosinophil migration Source: Ensembl
Positive regulation of ERK1 and ERK2 cascade Source: GO_Central
Positive regulation of GTPase activity Source: BHF-UCL
Positive regulation of inflammatory response Source: Ensembl
Regulation of cell shape Source: UniProtKB
Signal transduction Source: ProtInc
Cellular Location
Secreted
PTM
N-glycosylated.
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Anti-CCL24 antibodies
+ Filters

Target: CCL24
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXC-0120
Application*: E, WB
Target: CCL24
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-2969
Application*: E
Target: CCL24
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYC-0967
Application*: B, WB, E
Target: CCL24
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYM-0935
Application*: E, WB, IP
Target: CCL24
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 8C72
Application*: N, WB
Target: CCL24
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 2C5
Application*: E, WB
Target: CCL24
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 02
Application*: E
Target: CCL24
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: 8M17
Application*: N, WB
Target: CCL24
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 61016.11
Application*: WB
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(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot

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