CCL24

CCL24 (C-C Motif Chemokine Ligand 24) is a Protein Coding gene. Diseases associated with CCL24 include Allergic Asthma and Allergic Hypersensitivity Disease. Among its related pathways are PEDF Induced Signaling and Akt Signaling. Gene Ontology (GO) annotations related to this gene include cytokine activity and chemokine activity. An important paralog of this gene is CCL13.

C-C Motif Chemokine Ligand 24

Chemotactic for resting T-lymphocytes, and eosinophils (PubMed:9104803, PubMed:9365122).
Has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes (PubMed:9104803, PubMed:9365122).
Is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line (PubMed:9104803, PubMed:9365122).
Binds to CCR3 (PubMed:9104803, PubMed:9365122).

Cell-cell signaling Source: ProtInc
Cellular response to interferon-gamma Source: GO_Central
Cellular response to interleukin-1 Source: GO_Central
Cellular response to tumor necrosis factor Source: GO_Central
Chemokine-mediated signaling pathway Source: GO_Central
Chemotaxis Source: ProtInc
Cytoskeleton organization Source: UniProtKB
Eosinophil chemotaxis Source: UniProtKB
G protein-coupled receptor signaling pathway Source: GO_Central
Immune response Source: ProtInc
Inflammatory response Source: GO_Central
Lymphocyte chemotaxis Source: GO_Central
Monocyte chemotaxis Source: GO_Central
Neutrophil chemotaxis Source: GO_Central
Positive regulation of actin filament polymerization Source: BHF-UCL
Positive regulation of angiogenesis Source: Ensembl
Positive regulation of cell migration Source: BHF-UCL
Positive regulation of endothelial cell proliferation Source: BHF-UCL
Positive regulation of eosinophil migration Source: Ensembl
Positive regulation of ERK1 and ERK2 cascade Source: GO_Central
Positive regulation of GTPase activity Source: BHF-UCL
Positive regulation of inflammatory response Source: Ensembl
Regulation of cell shape Source: UniProtKB
Signal transduction Source: ProtInc

Secreted

N-glycosylated.