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CD58

CD58 (CD58 Molecule) is a Protein Coding gene. Diseases associated with CD58 include Whipple Disease and Oral Lichen Planus. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Innate Immune System. Gene Ontology (GO) annotations related to this gene include receptor binding.
Full Name
CD58 Molecule
Function
Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells.
Biological Process
Cell-cell adhesion Source: UniProtKB
Cellular response to interferon-gamma Source: UniProtKB
Cellular response to tumor necrosis factor Source: UniProtKB
Heterotypic cell-cell adhesion Source: UniProtKB
Leukocyte migration Source: Reactome
Neutrophil degranulation Source: Reactome
Positive regulation of interleukin-8 production Source: UniProtKB
Cellular Location
Cell membrane
Topology
Extracellular: 29-215
Helical: 216-238
Cytoplasmic: 239-250

Anti-CD58 antibodies

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Mouse Anti-CD58 Recombinant Antibody (A075) (CBMAB-AP10744LY)

Datasheet SDS
Target: CD58
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: A075
Application*: FC, IP

Mouse Anti-CD58 Recombinant Antibody (MEM-63) (CBMAB-AP1180LY)

Datasheet SDS
Target: CD58
Host: Mouse
Antibody Isotype: IgG1
Specificity: Dog, Human, Pig
Clone: MEM-63
Application*: FC

Mouse Anti-CD58 Recombinant Antibody (HI58a) (CBMAB-AO242LY)

Datasheet SDS
Target: CD58
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: HI58a
Application*: ELISA, FC

Mouse Anti-CD58 Recombinant Antibody (CB123) (CBMAB-CS123LY)

Datasheet SDS
Target: CD58
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CB123
Application*: IF, FC

Mouse Anti-CD58 Recombinant Antibody (CBXC-1847) (CBMAB-C4588-CQ)

Datasheet SDS
Target: CD58
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-1847
Application*: F

Mouse Anti-CD58 Recombinant Antibody (CBXC-0244) (CBMAB-C4585-CQ)

Datasheet SDS
Target: CD58
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXC-0244
Application*: F, WB

Mouse Anti-CD58 Recombinant Antibody (CBXC-0242) (CBMAB-C4584-CQ)

Datasheet SDS
Target: CD58
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-0242
Application*: F, IH, IP

Mouse Anti-CD58 Recombinant Antibody (CBXC-0241) (CBMAB-C4582-CQ)

Datasheet SDS
Target: CD58
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXC-0241
Application*: WB, SE, E

Mouse Anti-CD58 Recombinant Antibody (TS2/9) (CBMAB-C2080-CQ)

Datasheet SDS
Target: CD58
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: TS2/9
Application*: F

Mouse Anti-CD58 Recombinant Antibody (CBXC-1039) (CBMAB-C1303-CQ)

Datasheet SDS
Target: CD58
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXC-1039
Application*: F

Mouse Anti-CD58 (AA 1-240) Recombinant Antibody (CBFYC-1369) (CBMAB-C1427-FY)

Datasheet SDS
Target: CD58
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYC-1369
Application*: E, WB

Mouse Anti-CD58 Recombinant Antibody (CBFYC-0472) (CBMAB-C0518-FY)

Datasheet SDS
Target: CD58
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYC-0472
Application*: F

Mouse Anti-CD58 Recombinant Antibody (CBFYC-0381) (CBMAB-C0421-FY)

Datasheet SDS
Target: CD58
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Dog
Clone: CBFYC-0381
Application*: F

Mouse Anti-CD58 Recombinant Antibody (CBFYC-0168) (CBMAB-C0191-FY)

Datasheet SDS
Target: CD58
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-0168
Application*: F

Mouse Anti-CD58 Recombinant Antibody (CBFYC-0167) (CBMAB-C0190-FY)

Datasheet SDS
Target: CD58
Host: Mouse
Antibody Isotype: IgG1
Specificity: Sheep
Clone: CBFYC-0167
Application*: F, IP

Rabbit Anti-CD58 Recombinant Antibody (CBYJL-1015) (CBMAB-L0425-YJ)

Datasheet SDS
Target: CD58
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJL-1015
Application*: E

Rabbit Anti-CD58 Recombinant Antibody (083) (CBMAB-L0424-YJ)

Datasheet SDS
Target: CD58
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 083
Application*: F

Mouse Anti-CD58 Recombinant Antibody (CBYJL-146) (CBMAB-L0217-YJ)

Datasheet SDS
Target: CD58
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CBYJL-146
Application*: WB, IP, E, C, N, F, B, IC, IF

Mouse Anti-CD58 Recombinant Antibody (CBYJL-144) (CBMAB-L0215-YJ)

Datasheet SDS
Target: CD58
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Pig
Clone: CBYJL-144
Application*: F

Mouse Anti-CD58 Recombinant Antibody (CBYJL-140) (CBMAB-L0211-YJ)

Datasheet SDS
Target: CD58
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYJL-140
Application*: WB, P, IC, IF, E

Mouse Anti-CD58 Recombinant Antibody (CB122) (CBMAB-CS122LY)

Datasheet SDS
Target: CD58
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CB122
Application*: IF, FC

Mouse Anti-CD58 Recombinant Antibody (CB121) (CBMAB-CS121LY)

Datasheet SDS
Target: CD58
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CB121
Application*: IF, FC

Mouse Anti-CD58 Recombinant Antibody (MM0176-8G24) (CBMAB-C10506-LY)

Datasheet SDS
Target: CD58
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: MM0176-8G24
Application*: WB, F

Mouse Anti-CD58 Recombinant Antibody (VC21) (CBMAB-C10508-LY)

Datasheet SDS
Target: CD58
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rabbit
Clone: VC21
Application*: F

Mouse Anti-CD58 Recombinant Antibody (L180/1) (CBMAB-C10501-LY)

Datasheet SDS
Target: CD58
Host: Mouse
Antibody Isotype: IgG1
Specificity: Sheep
Clone: L180/1
Application*: F

Mouse Anti-CD58 Recombinant Antibody (BRIC-5) (CBMAB-C1860-CN)

Datasheet SDS
Target: CD58
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: BRIC-5
Application*: FC

Mouse Anti-CD58 Recombinant Antibody (14L224) (CBMAB-C1858-CN)

Datasheet SDS
Target: CD58
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: 14L224
Application*: FC, WB

Mouse Anti-CD58 Recombinant Antibody (B-L28) (CBMAB-C0496-CN)

Datasheet SDS
Target: CD58
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: B-L28
Application*: FC

Mouse Anti-CD58 Recombinant Antibody (CBYY-C1516) (CBMAB-C2954-YY)

Datasheet SDS
Target: CD58
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYY-C1516
Application*: F

Mouse Anti-CD58 Recombinant Antibody (CBYY-C1513) (CBMAB-C2951-YY)

Datasheet SDS
Target: CD58
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: CBYY-C1513
Application*: F, WB

Mouse Anti-CD58 Recombinant Antibody (CBYY-C0652) (CBMAB-C1943-YY)

Datasheet SDS
Target: CD58
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C0652
Application*: F

Mouse Anti-CD58 Recombinant Antibody (CBYY-C0267) (CBMAB-C0782-YY)

Datasheet SDS
Target: CD58
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C0267
Application*: IF, F

Mouse Anti-CD58 Recombinant Antibody (7H219) (CBMAB-C8830-LY)

Datasheet SDS
Target: CD58
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 7H219
Application*: F

Mouse Anti-CD58 Recombinant Antibody (5F69) (CBMAB-C7633-LY)

Datasheet SDS
Target: CD58
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5F69
Application*: F, IF

Mouse Anti-CD58 Recombinant Antibody (3H1578) (CBMAB-C6250-LY)

Datasheet SDS
Target: CD58
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 3H1578
Application*: C, WB

Mouse Anti-CD58 Recombinant Antibody (2D11-B10) (CBMAB-C4867-LY)

Datasheet SDS
Target: CD58
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2D11-B10
Application*: E, IF, P, WB

Mouse Anti-CD58 Recombinant Antibody (248310) (CBMAB-C0722-LY)

Datasheet SDS
Target: CD58
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 248310
Application*: WB, F, MC

Mouse Anti-CD58 Recombinant Antibody (1C3 ) (CBMAB-C0491-LY)

Datasheet SDS
Target: CD58
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1C3
Application*: F

Mouse Anti-CD58 Recombinant Antibody (10B1840) (CBMAB-C0150-LY)

Datasheet SDS
Target: CD58
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 10B1840
Application*: F, IH, IP

Mouse Anti-CD58 Recombinant Antibody (10B1838) (CBMAB-C0149-LY)

Datasheet SDS
Target: CD58
Host: Mouse
Antibody Isotype: IgG1
Specificity: Sheep
Clone: 10B1838
Application*: F, IP

CD58 Matched Antibody Pair (231) (APMAB-231LY)

Datasheet SDS
Target: CD58
Specificity: Human
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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