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CD58 Matched Antibody Pair (231) (APMAB-231LY)

This antibody pair set can be used for detecting and quantifying protein level of human CD58.
See all CD58 antibodies

Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Mouse anti-CD58 monoclonal antibody, 100 ug
Detection Antibody
Anti-CD58 Rabbit polyclonal antibody, 50 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
CD58 (CD58 Molecule) is a Protein Coding gene. Diseases associated with CD58 include Whipple Disease and Oral Lichen Planus. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Innate Immune System. Gene Ontology (GO) annotations related to this gene include receptor binding.
Alternative Names
CD58 Molecule; CD58 Antigen, (Lymphocyte Function-Associated Antigen 3); Surface Glycoprotein LFA-3; LFA3; AG3; Lymphocyte Function-Associated Antigen 3; CD58 Antigen; LFA-3;
Entrez Gene ID
965
UniProt ID
P19256

Zhang, Y., Liu, Q., Yang, S., & Liao, Q. (2021). CD58 Immunobiology at a Glance. Frontiers in Immunology, 12, 2212.

Zhang, Y., Liu, Q., Liu, J., & Liao, Q. (2021). Upregulated CD58 is associated with clinicopathological characteristics and poor prognosis of patients with pancreatic ductal adenocarcinoma. Cancer Cell International, 21(1), 1-15.

Tripathi, N., Leherte, L., Vercauteren, D. P., & Laurent, A. D. (2021). Structure-based identification of inhibitors disrupting the CD2–CD58 interactions. Journal of computer-aided molecular design, 35(3), 337-353.

Parajuli, P., Sable, R., Shrestha, L., Dahal, A., Gauthier, T., Taneja, V., & Jois, S. (2021). Modulation of co‐stimulatory signal from CD2–CD58 proteins by a grafted peptide. Chemical Biology & Drug Design, 97(3), 607-627.

Otsuka, Y., Nishikori, M., Arima, H., Izumi, K., Kitawaki, T., Hishizawa, M., & Takaori-Kondo, A. (2020). EZH2 inhibitors restore epigenetically silenced CD58 expression in B-cell lymphomas. Molecular immunology, 119, 35-45.

Yamamoto, M., Watanabe, M., Inoue, N., Watanabe, A., Ozaki, H., Ohsaki, M., ... & Iwatani, Y. (2020). Association of CD58 polymorphisms and its protein expression with the development and prognosis of autoimmune thyroid diseases. Immunological investigations, 49(1-2), 106-119.

Veldman, J., Visser, L., Huberts-Kregel, M., Muller, N., Hepkema, B., Van den Berg, A., & Diepstra, A. (2020). Rosetting T cells in Hodgkin lymphoma are activated by immunological synapse components HLA class II and CD58. Blood, 136(21), 2437-2441.

Leherte, L., Petit, A., Jacquemin, D., Vercauteren, D. P., & Laurent, A. D. (2018). Investigating cyclic peptides inhibiting CD2–CD58 interactions through molecular dynamics and molecular docking methods. Journal of computer-aided molecular design, 32(11), 1295-1313.

Lu, Y. J., Qiu, L. L., & Wang, L. L. (2017). Research Progress on Relationship between CD58 Molecule and ALL and Lymphoma-Review. Zhongguo shi yan xue ye xue za zhi, 25(2), 592-595.

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For research use only. Not intended for any clinical use.

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