CDC37

CDC37 (Cell Division Cycle 37) is a Protein Coding gene. Among its related pathways are Aryl Hydrocarbon Receptor and Signaling by Ligand-Responsive EGFR Variants in Cancer. Gene Ontology (GO) annotations related to this gene include protein kinase binding and kinase binding. An important paralog of this gene is CDC37L1.
Full Name
Cell Division Cycle 37
Function
Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity (PubMed:8666233).
Inhibits HSP90AA1 ATPase activity (PubMed:23569206).
Biological Process
ERBB2 signaling pathway Source: Reactome
Positive regulation of mitophagy in response to mitochondrial depolarization Source: Ensembl
Posttranscriptional regulation of gene expression Source: Ensembl
Protein folding Source: GO_Central
Protein stabilization Source: GO_Central
Protein targeting Source: ProtInc
Regulation of cyclin-dependent protein serine/threonine kinase activity Source: ProtInc
Regulation of interferon-gamma-mediated signaling pathway Source: MGI
Regulation of necroptotic process Source: Reactome
Regulation of type I interferon-mediated signaling pathway Source: MGI
Cellular Location
Cytoplasm
PTM
Constitutively sumoylated by UBE2I.
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Anti-CDC37 antibodies

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Mouse Anti-CDC37 Recombinant Antibody (AP1357) (CBMAB-AP1357LY)

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Target: CDC37
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: AP1357
Application*: WB, IF, IP, P, E
Datasheet SDS

Rabbit Anti-CDC37 Recombinant Antibody (CBNH-126) (CBMAB-R4451-CN)

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Target: CDC37
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBNH-126
Application*: F, IP, IF, WB
Datasheet SDS

Mouse Anti-CDC37 Recombinant Antibody (CBFYC-1518) (CBMAB-C1577-FY)

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Target: CDC37
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Mouse, Rat
Clone: CBFYC-1518
Application*: WB, IF, IP, P, E
Datasheet SDS

Mouse Anti-CDC37 Recombinant Antibody (3C7) (CBMAB-C5824-LY)

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Target: CDC37
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: 3C7
Application*: WB, E, IH, IF
Datasheet SDS

Rabbit Anti-CDC37 Recombinant Antibody (
10C3) (V2LY-0725-LY1540)

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Target: CDC37
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 10C3
Application*: E, WB, F
Datasheet SDS

Mouse Anti-CDC37 Recombinant Antibody (CBT2976) (V2LY-0625-LY647)

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Target: CDC37
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Mouse
Clone: CBT2976
Application*: WB, F
Datasheet SDS

Mouse Anti-CDC37 Recombinant Antibody (CBT3739) (V2LY-0625-LY646)

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Target: CDC37
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBT3739
Application*: WB
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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