CDKN3

Cyclin-dependent kinase inhibitor 3 (CDKN3) has been reported to promote tumor genesis.
Full Name
Cyclin Dependent Kinase Inhibitor 3
Function
May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues. Dephosphorylates CDK2 at 'Thr-160' in a cyclin-dependent manner.
Biological Process
Cell cycle arrest Source: MGI
G1/S transition of mitotic cell cycle Source: ProtInc
Negative regulation of cell population proliferation Source: ProtInc
Regulation of cyclin-dependent protein serine/threonine kinase activity Source: ProtInc
Cellular Location
Perinuclear region
Involvement in disease
Hepatocellular carcinoma (HCC): A primary malignant neoplasm of epithelial liver cells. The major risk factors for HCC are chronic hepatitis B virus (HBV) infection, chronic hepatitis C virus (HCV) infection, prolonged dietary aflatoxin exposure, alcoholic cirrhosis, and cirrhosis due to other causes.
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Anti-CDKN3 antibodies

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Mouse Anti-CDKN3 Recombinant Antibody (CBXC-2098) (CBMAB-C5410-CQ)

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Target: CDKN3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CBXC-2098
Application*: WB, IF
Datasheet SDS

Mouse Anti-CDKN3 Recombinant Antibody (CBYY-C1818) (CBMAB-C3256-YY)

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Target: CDKN3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CBYY-C1818
Application*: F, IF, WB
Datasheet SDS

Rabbit Anti-CDKN3 Recombinant Antibody (CBFYC-1652) (CBMAB-C1713-FY)

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Target: CDKN3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBFYC-1652
Application*: WB, IP
Datasheet SDS

Mouse Anti-CDKN3 Recombinant Antibody (CBFYC-1651) (CBMAB-C1712-FY)

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Target: CDKN3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat, Dog
Clone: CBFYC-1651
Application*: WB, IP, IF
Datasheet SDS

Mouse Anti-CDKN3 Recombinant Antibody (2H1) (CBMAB-C5236-LY)

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Target: CDKN3
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Mouse
Clone: 2H1
Application*: F, IH, WB
Datasheet SDS

Rabbit Anti-CDKN3 (Phospho-Thr14) Recombinant Antibody (CBLY1-019) (CBMAB-K0284-LY)

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Target: CDKN3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBLY1-019
Application*: E, WB
Datasheet SDS
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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