CEACAM8

CEACAM8 (Carcinoembryonic Antigen Related Cell Adhesion Molecule 8) is a Protein Coding gene. Diseases associated with CEACAM8 include Endocarditis and Shwartzman Phenomenon. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. An important paralog of this gene is CEACAM6.
Full Name
Carcinoembryonic Antigen Related Cell Adhesion Molecule 8
Function
Cell surface glycoprotein that plays a role in cell adhesion in a calcium-independent manner (PubMed:8776764, PubMed:2022629, PubMed:11590190).
Mediates heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6 (PubMed:8776764, PubMed:2022629, PubMed:11590190).
Heterophilic interaction with CEACAM8 occurs in activated neutrophils (PubMed:8776764).
Biological Process
Heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules Source: UniProtKB
Immune response Source: ProtInc
Leukocyte migration Source: Reactome
Neutrophil degranulation Source: Reactome
Cellular Location
Cell membrane; Cell surface
PTM
Glycosylated.
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Anti-CEACAM8 antibodies

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Target: CEACAM8
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 6/40c
Application*: WB, F, E, IH, IP
Target: CEACAM8
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C1859
Application*: F, IH, WB
Target: CEACAM8
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C0204
Application*: F, IH, IF
Target: CEACAM8
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 13
Application*: E
Target: CEACAM8
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4
Application*: E, WB
Target: CEACAM8
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2370
Application*: WB
Target: CEACAM8
Host: Human
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-0798
Application*: F, IH, IF
Target: CEACAM8
Host: Mouse
Antibody Isotype: IgM, κ
Specificity: Human, Mouse
Clone: CBXC-1352
Application*: F, IH, IF
Target: CEACAM8
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYC-0064
Application*: WB, IP, F, E
More Infomation
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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