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Mouse Anti-CEACAM8 Recombinant Antibody (CBT2370) (V2LY-0625-LY1009)

Tested Data

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBT2370
Antibody Isotype
IgG1
Application
WB

Basic Information

Immunogen
Purified recombinant fragment of human CD66B (AA: 43-178) expressed in E. Coli.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
WB1:500-1:2,000
ELISA1:10,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
Sodium azide
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Carcinoembryonic Antigen Related Cell Adhesion Molecule 8
Entrez Gene ID
UniProt ID
Function
Cell surface glycoprotein that plays a role in cell adhesion in a calcium-independent manner (PubMed:8776764, PubMed:2022629, PubMed:11590190).
Mediates heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6 (PubMed:8776764, PubMed:2022629, PubMed:11590190).
Heterophilic interaction with CEACAM8 oCcurs in activated neutrophils (PubMed:8776764).
Biological Process
Heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules Source: UniProtKB
Immune response Source: ProtInc
Leukocyte migration Source: Reactome
Neutrophil degranulation Source: Reactome
Cellular Location
Cell membrane; Cell surface
PTM
Glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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