CLIC3

Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 3 is a member of the p64 family and is predominantly localized in the nucleus and stimulates chloride ion channel activity. In addition, this protein may participate in cellular growth control, based on its association with ERK7, a member of the MAP kinase family. [provided by RefSeq, Jul 2008]
Full Name
Chloride Intracellular Channel 3
Function
Can insert into membranes and form chloride ion channels. May participate in cellular growth control.
Biological Process
Chloride transport Source: UniProtKB
Glutathione metabolic process Source: InterPro
Regulation of ion transmembrane transport Source: UniProtKB-KW
Signal transduction Source: ProtInc
Cellular Location
Nucleus; Cytoplasm; Membrane. Predominantly nuclear. Some protein was found in the cytoplasm. Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain (By similarity).
Topology
Helical: 24-44
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Anti-CLIC3 antibodies

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Mouse Anti-CLIC3 Recombinant Antibody (CBCNC-024) (CBMAB-C0917-CN)

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Target: CLIC3
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Mouse, Rat
Clone: CBCNC-024
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-CLIC3 Recombinant Antibody (CBWJC-2796) (V2LY-1206-LY223)

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Target: CLIC3
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBWJC-2796
Application*: WB, IP, IF, E, P
Datasheet SDS

Mouse Anti-CLIC3 Recombinant Antibody (CBYY-C3155) (V2LY-1206-LY222)

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Target: CLIC3
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYY-C3155
Application*: WB, IP, IF, E, P
Datasheet SDS

Mouse Anti-CLIC3 Recombinant Antibody (2C5) (V2LY-1206-LY221)

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Target: CLIC3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 2C5
Application*: E, WB
Datasheet SDS

CLIC3 Matched Antibody Pair (277) (APMAB-277LY)

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Target: CLIC3
Specificity: Human
Datasheet SDS

CLIC3 Matched Antibody Pair (276) (APMAB-276LY)

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Target: CLIC3
Specificity: Human
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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