CLIC3 Matched Antibody Pair (276) (APMAB-276LY)

Name: CLIC3 Matched Antibody Pair (276)
SKU: APMAB-276LY
Rating: 5 (1 reviews)

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Datasheet

Specifications

ApplIcation

Sandwich ELISA

Specificity

Human

Capture Antibody

Rabbit anti-CLIC3 polyclonal antibody, 100 ug

Detection Antibody

Anti-CLIC3 Mouse polyclonal antibody, 20 ug

Dilutions

10 ng/ml-100 ng/ml

Format

Liquid

Storage

Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.

Introduction

Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 3 is a member of the p64 family and is predominantly localized in the nucleus and stimulates chloride ion channel activity. In addition, this protein may participate in cellular growth control, based on its association with ERK7, a member of the MAP kinase family. [provided by RefSeq, Jul 2008]

Alternative Names

Chloride Intracellular Channel 3;

Entrez Gene ID

9022

UniProt ID

O95833

More Infomation

References

Kawai, S., Fujii, T., Shimizu, T., Sukegawa, K., Hashimoto, I., Okumura, T., ... & Fujii, T. (2020). Pathophysiological properties of CLIC3 chloride channel in human gastric cancer cells. The Journal of Physiological Sciences, 70(1), 1-11.

Chen, M., Zhang, S., Wen, X., Cao, H., & Gao, Y. (2020). Prognostic value of CLIC3 mRNA overexpression in bladder cancer. PeerJ, 8, e8348.

Liang, J., Long, Z., Zhang, Y., Chen, X., Zhang, T., Hu, Z., ... & Zheng, Y. (2019). Polarization to Anti-Inflammatory Status of Macrophages Predicts Poor Prognosis of HBV-Related Acute-on-Chronic Liver Failure Patients via Chloride Intercellular Channel 3 Suppression. Available at SSRN 3363780.

Hernandez-Fernaud, J. R., Ruengeler, E., Casazza, A., Neilson, L. J., Pulleine, E., Santi, A., ... & Zanivan, S. (2017). Secreted CLIC3 drives cancer progression through its glutathione-dependent oxidoreductase activity. Nature communications, 8(1), 1-17.

Norman, J., & Zanivan, S. (2017). Chloride intracellular channel 3: A secreted pro-invasive oxidoreductase. Cell Cycle, 16(21), 1993-1994.

Brum, A. M., van der Leije, C. S., Schreuders‐Koedam, M., Verhoeven, J., Janssen, M., Dekkers, D. H., ... & van der Eerden, B. C. (2017). Identification of chloride intracellular channel protein 3 as a novel gene affecting human bone formation. JBMR plus, 1(1), 16-26.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

Alternative Versions

CLIC3 Matched Antibody Pair (277)

Antibody Pairs

CLIC3 Matched Antibody Pair (277)

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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