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CSF2RA

CSF2RA (Colony Stimulating Factor 2 Receptor Alpha Subunit) is a Protein Coding gene. Diseases associated with CSF2RA include Surfactant Metabolism Dysfunction, Pulmonary, 4 and Hereditary Pulmonary Alveolar Proteinosis. Among its related pathways are RET signaling and Cytokine Signaling in Immune system. Gene Ontology (GO) annotations related to this gene include receptor activity and cytokine receptor activity. An important paralog of this gene is IL3RA.

Full Name

Colony Stimulating Factor 2 Receptor Alpha Subunit

Function

Low affinity receptor for granulocyte-macrophage colony-stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells.

Biological Process

Cellular protein metabolic process Source: Reactome
Cytokine-mediated signaling pathway Source: GO_Central
MAPK cascade Source: Reactome

Cellular Location

Cell membrane
Isoform 3&4&6: Secreted

Involvement in disease

Pulmonary surfactant metabolism dysfunction 4 (SMDP4):
A rare lung disorder due to impaired surfactant homeostasis. It is characterized by alveolar filling with floccular material that stains positive using the periodic acid-Schiff method and is derived from surfactant phospholipids and protein components. Excessive lipoproteins accumulation in the alveoli results in severe respiratory distress.

Topology

Extracellular: 23-320
Helical: 321-346
Cytoplasmic: 347-400

Anti-CSF2RA antibodies

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Rabbit Anti-CSF2RA Recombinant Antibody (EG840) (V2LY-1206-LY1450)

SDS

Target: CSF2RA

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: EG840

Application*: E

Mouse Anti-CSF2RA Recombinant Antibody (AP1734) (V2LY-1206-LY1449)

SDS

Target: CSF2RA

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: AP1734

Application*: F

Rabbit Anti-CSF2RA Recombinant Antibody (14L270) (V2LY-1206-LY1448)

SDS

Target: CSF2RA

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: 14L270

Application*: E, F

Human Anti-CSF2RA Recombinant Antibody (CBWJC-3183) (V2LY-1206-LY1447)

SDS

Target: CSF2RA

Host: Human

Antibody Isotype: IgG4

Specificity: Human

Clone: CBWJC-3183

Application*: F

Mouse Anti-CSF2RA Recombinant Antibody (CBWJC-3182) (V2LY-1206-LY1446)

SDS

Target: CSF2RA

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBWJC-3182

Application*: E

Mouse Anti-CSF2RA Recombinant Antibody (CBWJC-2070) (V2LY-1206-LY1445)

SDS

Target: CSF2RA

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBWJC-2070

Application*: F, WB

Mouse Anti-CSF2RA Recombinant Antibody (CBXC-0584) (V2LY-1206-LY1444)

SDS

Target: CSF2RA

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human, Mouse, Rat

Clone: CBXC-0584

Application*: WB, IP, IF, F

Mouse Anti-CSF2RA Recombinant Antibody (CBXC-2563) (V2LY-1206-LY1443)

SDS

Target: CSF2RA

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBXC-2563

Application*: WB, IP, IF, E

Human Anti-CSF2RA Recombinant Antibody (CBXC-0747) (V2LY-1206-LY1442)

SDS

Target: CSF2RA

Host: Human

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXC-0747

Application*: F

Mouse Anti-CSF2RA Recombinant Antibody (CBYY-C2892) (V2LY-1206-LY1441)

SDS

Target: CSF2RA

Host: Mouse

Antibody Isotype: IgG3, κ

Specificity: Human

Clone: CBYY-C2892

Application*: WB, IP, IF, E

Rat Anti-CSF2RA Recombinant Antibody (CBFYH-3359) (V2LY-1206-LY1440)

SDS

Target: CSF2RA

Host: Rat

Antibody Isotype: IgG2a

Specificity: Mouse

Clone: CBFYH-3359

Application*: F, N, IF

Mouse Anti-CSF2RA Recombinant Antibody (CBLG1-3130) (V2LY-1206-LY1439)

SDS

Target: CSF2RA

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human, Mouse, Rat

Clone: CBLG1-3130

Application*: WB, IP

Mouse Anti-CSF2RA Recombinant Antibody (G1417) (V2LY-1206-LY1438)

SDS

Target: CSF2RA

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: G1417

Application*: WB

Mouse Anti-CSF2RA Recombinant Antibody (2G5) (V2LY-1206-LY1437)

SDS

Target: CSF2RA

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 2G5

Application*: E, WB

Mouse Anti-CSF2RA Recombinant Antibody (CBFYH-0105) (V2LY-1206-LY1436)

SDS

Target: CSF2RA

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human, Mouse, Rat

Clone: CBFYH-0105

Application*: WB, IP, IF, F

Mouse Anti-CSF2RA Recombinant Antibody (CBFYH-0106) (V2LY-1206-LY1435)

SDS

Target: CSF2RA

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human, Mouse, Rat

Clone: CBFYH-0106

Application*: WB, IP, IF, F

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)

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