Human CSF2RA ELISA Kit (V2LY-0626-LY4636)

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Tested Data
Datasheet
SDS
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Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity
0.0054 ng/mL
Detection Range
0.01-2 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Human
Assay Type
Sandwich
Reactivity
Human
Assay Time
1.5 h
Molecule Mass
46.2 kDa
Components
  • Pre-coated ELISA plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
Colony Stimulating Factor 2 Receptor Alpha Subunit
Function
Low affinity receptor for granulocyte-macrophage colony-stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells.
Biological Process
Cellular protein metabolic process Source: Reactome
Cytokine-mediated signaling pathway Source: GO_Central
MAPK cascade Source: Reactome
Cellular Location
Cell membrane
Isoform 3&4&6: Secreted
Involvement in disease
Pulmonary surfactant metabolism dysfunction 4 (SMDP4):
A rare lung disorder due to impaired surfactant homeostasis. It is characterized by alveolar filling with floccular material that stains positive using the periodic acid-Schiff method and is derived from surfactant phospholipids and protein components. Excessive lipoproteins accumulation in the alveoli results in severe respiratory distress.
Topology
Extracellular: 23-320
Helical: 321-346
Cytoplasmic: 347-400

Xiao, Y., Uh, K., Negrón-Pérez, V. M., Haines, H., Lee, K., & Hansen, P. J. (2021). Regulation of gene expression in the bovine blastocyst by colony-stimulating factor 2 is disrupted by CRISPR/Cas9-mediated deletion of CSF2RA. Biology of Reproduction, 104(5), 995-1007.

Xiao, Y., Uh, K., Negrón-Pérez, V. M., Haines, H., Lee, K., & Hansen, P. J. (2021). Regulation of gene expression in the bovine blastocyst by CSF2 is disrupted by CRISPR/Cas9-mediated deletion of CSF2RA. Biology of Reproduction.

Sinkey, R. G., Guzeloglu-Kayisli, O., Arlier, S., Guo, X., Semerci, N., Moore, R., ... & Lockwood, C. J. (2020). Thrombin-induced decidual colony-stimulating factor-2 promotes abruption-related preterm birth by weakening fetal membranes. The American journal of pathology, 190(2), 388-399.

Huang, R., Cao, Y., Li, H., Hu, Z., Zhang, H., Zhang, L., ... & Li, X. (2020). miR-532-3p-CSF2RA axis as a key regulator of vulnerable atherosclerotic plaque formation. Canadian Journal of Cardiology, 36(11), 1782-1794.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Human Recombinant CSF2RA protein, hFc Tag (CAT#: V2LY-0526-LY4357)

Human Recombinant CSF2RA protein, His Tag (CAT#: V2LY-0526-LY4358)

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Mouse Anti-CSF2RA Recombinant Antibody (CBFYH-0106) (CAT#: V2LY-1206-LY1435)

Mouse Anti-CSF2RA Recombinant Antibody (CBFYH-0105) (CAT#: V2LY-1206-LY1436)

Human Recombinant CSF2RA protein, hFc Tag (CAT#: V2LY-0526-LY4357)

Rat Anti-CSF2RA Recombinant Antibody (CBFYH-3359) (CAT#: V2LY-1206-LY1440)

Rabbit Anti-CSF2RA Recombinant Antibody (EG840) (CAT#: V2LY-1206-LY1450)

Human Anti-CSF2RA Recombinant Antibody (CBWJC-3183) (CAT#: V2LY-1206-LY1447)

Human Recombinant CSF2RA protein, His Tag (CAT#: V2LY-0526-LY4358)

Mouse Anti-CSF2RA Recombinant Antibody (CBYY-C2892) (CAT#: V2LY-1206-LY1441)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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