CSF2RB

CSF2RB (Colony Stimulating Factor 2 Receptor Beta Common Subunit) is a Protein Coding gene. Diseases associated with CSF2RB include Surfactant Metabolism Dysfunction, Pulmonary, 5 and Hereditary Pulmonary Alveolar Proteinosis. Among its related pathways are RET signaling and PEDF Induced Signaling. Gene Ontology (GO) annotations related to this gene include receptor activity and interleukin-3 receptor activity.

Colony Stimulating Factor 2 Receptor Beta Common Subunit

High affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor.

Cellular protein metabolic process Source: Reactome
Cellular response to interleukin-3 Source: GOC
Cytokine-mediated signaling pathway Source: Reactome
Interleukin-3-mediated signaling pathway Source: GOC
Interleukin-5-mediated signaling pathway Source: GOC
MAPK cascade Source: Reactome
Respiratory gaseous exchange by respiratory system Source: ProtInc
Response to lipopolysaccharide Source: Ensembl
Signal transduction Source: UniProtKB

Membrane

Pulmonary surfactant metabolism dysfunction 5 (SMDP5):
A rare lung disorder due to impaired surfactant homeostasis. It is characterized by alveolar filling with floccular material that stains positive using the periodic acid-Schiff method and is derived from surfactant phospholipids and protein components. Excessive lipoproteins accumulation in the alveoli results in severe respiratory distress.

Extracellular: 17-443
Helical: 444-460
Cytoplasmic: 461-897

May be phosphorylated by LYN.