Human Recombinant IL3RB protein, His Tag (V2LY-0526-LY4919)

Name: Human Recombinant IL3RB protein, His Tag
SKU: V2LY-0526-LY4919
Rating: 5 (1 reviews)

See all CSF2RB antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Expressed Host

HEK293 Cells

Protein Species

Human

Tag

His Tag

Protein Construction

This product is Human Recombinant IL3RB protein, His Tag consist of Amino Acid: 1-443 and predicts a molecular mass of 50 kDa.

Molecule Mass

50 kDa

Verified

HPLC

Sequence

Amino Acid: 1-443

Species

Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity

≥97% as determined by SDS-PAGE. ≥90% as determined by SEC-HPLC.

Endotoxin

Please contact us for more information.

Format

Lyophilized

Reconstitution

Allow the vial and reconstitution buffer to equilibrate to room temperature. Briefly centrifuge or tap down the vial to ensure that all lyophilized powder is collected at the bottom of the vial. For the reconstitution of this product, we recommend adding PBS or sterile water to achieve a final antibody concentration of 1 mg/mL. Allow the vial to reconstitute for 10-15 minutes at room temperature with gentle agitation. Avoid vigorous shaking that can cause foaming and antibody denaturation. Aliquot into volumes based on your experiment and store liquid protein at -20°C or -80°C for long time.

Buffer

Lyophilized from sterile PBS

Preservative

None

Storage

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

More Infomation

Target

Full Name

Colony Stimulating Factor 2 Receptor Beta Common Subunit

Function

High affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor.

Biological Process

Cellular protein metabolic process Source: Reactome
Cellular response to interleukin-3 Source: GOC
Cytokine-mediated signaling pathway Source: Reactome
Interleukin-3-mediated signaling pathway Source: GOC
Interleukin-5-mediated signaling pathway Source: GOC
MAPK cascade Source: Reactome
Respiratory gaseous exchange by respiratory system Source: ProtInc
Response to lipopolysaccharide Source: Ensembl
Signal transduction Source: UniProtKB

Cellular Location

Membrane

Involvement in disease

Pulmonary surfactant metabolism dysfunction 5 (SMDP5):
A rare lung disorder due to impaired surfactant homeostasis. It is characterized by alveolar filling with floccular material that stains positive using the periodic acid-Schiff method and is derived from surfactant phospholipids and protein components. Excessive lipoproteins accumulation in the alveoli results in severe respiratory distress.

Topology

Extracellular: 17-443
Helical: 444-460
Cytoplasmic: 461-897

PTM

May be phosphorylated by LYN.

Rashid, M., Ali, R., Almuzzaini, B., Song, H., AlHallaj, A., Abdulkarim, A. A., ... & Boudjelal, M. (2021). Discovery of a novel potentially transforming somatic mutation in CSF2RB gene in breast cancer. Cancer medicine, 10(22), 8138-8150.

Schulte, V., Sipol, A., Burdach, S., & Rieger-Fackeldey, E. (2021). The Truncated Splice Variant of the Granulocyte-Macrophage-Colony-Stimulating Factor Receptor β-Chain in Peripheral Blood Serves as Severity Biomarker of Respiratory Failure in Newborns. Neonatology, 118(2), 187-193.

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Human Recombinant IL3RB protein, His Tag?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Human Recombinant EPOR & CD131 protein, Hetero Dimer , hFc Tag (CAT#: V2LY-0526-LY3933)

Rat Recombinant IL3RB protein, hFc Tag (CAT#: V2LY-0526-LY9478)

Related Products

Mouse Anti-CSF2RB Recombinant Antibody (CBYY-C3050) (CAT#: V2LY-1206-LY1459)

Rabbit Anti-CSF2RB Recombinant Antibody (CBFYC-2285) (CAT#: V2LY-1206-LY1455)

Mouse Anti-CSF2RB Recombinant Antibody (CBXC-1906) (CAT#: V2LY-1206-LY1462)

Human Recombinant EPOR & CD131 protein, Hetero Dimer , hFc Tag (CAT#: V2LY-0526-LY3933)

Mouse Anti-CSF2RB Recombinant Antibody (CBYY-C2159) (CAT#: V2LY-1206-LY1457)

Mouse Anti-CSF2RB Recombinant Antibody (CBXC-1926) (CAT#: V2LY-1206-LY1461)

Human Anti-CSF2RB Recombinant Antibody (CBXC-2553) (CAT#: V2LY-1206-LY1463)

Mouse Anti-CSF2RB Recombinant Antibody (CBT4570) (CAT#: V2LY-0625-LY1352)

Mouse Anti-CSF2RB Recombinant Antibody (CBYY-C0068) (CAT#: V2LY-1206-LY1456)

Mouse Anti-CSF2RB Recombinant Antibody (CBYY-I0216) (CAT#: V2LY-1206-LY1452)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry