Human Anti-CSF2RB Recombinant Antibody (CBXC-2553) (V2LY-1206-LY1463)

Name: Human Anti-CSF2RB Recombinant Antibody (CBXC-2553)
SKU: V2LY-1206-LY1463
Rating: 5 (1 reviews)

See all CSF2RB antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Human

Clone

CBXC-2553

Application

ELISA

Immunogen

Recombinant Human CSF2RB protein.

Host Species

Human

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal Antibody

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.4, 50% glycerol

Preservative

0.03% sodium azide

Concentration

1 mg/ml

Purity

>95% as determined by analysis by SDS-PAGE

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

Colony Stimulating Factor 2 Receptor Beta Common Subunit

Entrez Gene ID

1439

UniProt ID

P32927

Function

High affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor.

Biological Process

Cellular protein metabolic process Source: Reactome
Cellular response to interleukin-3 Source: GOC
Cytokine-mediated signaling pathway Source: Reactome
Interleukin-3-mediated signaling pathway Source: GOC
Interleukin-5-mediated signaling pathway Source: GOC
MAPK cascade Source: Reactome
Respiratory gaseous exchange by respiratory system Source: ProtInc
Response to lipopolysaccharide Source: Ensembl
Signal transduction Source: UniProtKB

Cellular Location

Membrane

Involvement in disease

Pulmonary surfactant metabolism dysfunction 5 (SMDP5):
A rare lung disorder due to impaired surfactant homeostasis. It is characterized by alveolar filling with floccular material that stains positive using the periodic acid-Schiff method and is derived from surfactant phospholipids and protein components. Excessive lipoproteins accumulation in the alveoli results in severe respiratory distress.

Topology

Extracellular: 17-443
Helical: 444-460
Cytoplasmic: 461-897

PTM

May be phosphorylated by LYN.

Rashid, M., Ali, R., Almuzzaini, B., Song, H., AlHallaj, A., Abdulkarim, A. A., ... & Boudjelal, M. (2021). Discovery of a novel potentially transforming somatic mutation in CSF2RB gene in breast cancer. Cancer medicine, 10(22), 8138-8150.

Schulte, V., Sipol, A., Burdach, S., & Rieger-Fackeldey, E. (2021). The Truncated Splice Variant of the Granulocyte-Macrophage-Colony-Stimulating Factor Receptor β-Chain in Peripheral Blood Serves as Severity Biomarker of Respiratory Failure in Newborns. Neonatology, 118(2), 187-193.

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Human Anti-CSF2RB Recombinant Antibody (CBXC-2553)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Anti-CSF2RB Recombinant Antibody (7D20) (CAT#: V2LY-1206-LY1451)

Rabbit Anti-CSF2RB Recombinant Antibody (CBFYC-2285) (CAT#: V2LY-1206-LY1455)

Human Anti-CSF2RB Recombinant Antibody (
7B6) (CAT#: V2LY-0725-LY678)

Human Recombinant IL3RB protein, His Tag (CAT#: V2LY-0526-LY4919)

Mouse Anti-CSF2RB Recombinant Antibody (CBXC-1926) (CAT#: V2LY-1206-LY1461)

Human Anti-CSF2RB Recombinant Antibody (CBXC-0735) (CAT#: V2LY-1206-LY1460)

Mouse Anti-CSF2RB Recombinant Antibody (CBT2722) (CAT#: V2LY-0625-LY1351)

Mouse Anti-CSF2RB Recombinant Antibody (CBYY-C2160) (CAT#: CBMAB-C3598-YY)

Mouse Anti-CSF2RB Recombinant Antibody (CBXC-1906) (CAT#: V2LY-1206-LY1462)

Mouse Anti-CSF2RB Recombinant Antibody (CBFYC-0024) (CAT#: V2LY-1206-LY1454)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry