CTSZ

CTSZ (Cathepsin Z) is a Protein Coding gene. Diseases associated with CTSZ include Dacryoadenitis. Among its related pathways are Peptide hormone metabolism and Clathrin derived vesicle budding. Gene Ontology (GO) annotations related to this gene include cysteine-type peptidase activity. An important paralog of this gene is CTSC.
Full Name
Cathepsin Z
Function
Exhibits carboxy-monopeptidase as well as carboxy-dipeptidase activity (PubMed:10504234).

Capable of producing kinin potentiating peptides (By similarity).
Biological Process
Angiotensin maturation Source: Reactome
COPII vesicle coating Source: Reactome
Endoplasmic reticulum to Golgi vesicle-mediated transport Source: Reactome
Negative regulation of plasminogen activation Source: CAFA
Negative regulation of protein binding Source: CAFA
Neutrophil degranulation Source: Reactome
Proteolysis Source: CAFA
Proteolysis involved in cellular protein catabolic process Source: GO_Central
Regulation of neuron death Source: CAFA
Cellular Location
Lysosome
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Anti-CTSZ antibodies

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Target: CTSZ
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat, Pig
Clone: CBFYC-2465
Application*: WB, IP, IF, E, P
Target: CTSZ
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYC-2464
Application*: WB, IF, F, E
Target: CTSZ
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 05
Application*: E
Target: CTSZ
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: 009
Application*: E, IF
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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