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DPH2

This gene is one of two human genes similar to the yeast gene dph2. The yeast gene was identified by its ability to complement a diphthamide mutant strain, and thus probably functions in diphthamide biosynthesis. Diphthamide is a post-translationally modified histidine residue present in elongation factor 2 (EF2) that is the target of diphtheria toxin ADP-ribosylation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Full Name
DPH2 homolog (S. cerevisiae)
Function
Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2).
Biological Process
Peptidyl-diphthamide biosynthetic process from peptidyl-histidine Source: GO_Central
Cellular Location
Cytosol
Topology
Extracellular: 30-448
Helical: 449-469
Cytoplasmic: 470-517
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Anti-DPH2 antibodies

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Mouse Anti-DPH2 Recombinant Antibody (5B10) (CBMAB-D1557-YC)

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Target: DPH2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 5B10
Application*: E, IF, WB
Datasheet SDS

Mouse Anti-DPH2 Recombinant Antibody (4E7) (CBMAB-D1556-YC)

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Target: DPH2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4E7
Application*: WB, P, F
Datasheet SDS

Mouse Anti-DPH2 Recombinant Antibody (4D9) (CBMAB-D1555-YC)

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Target: DPH2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4D9
Application*: P, WB
Datasheet SDS

Mouse Anti-DPH2 Recombinant Antibody (3F7) (CBMAB-D1554-YC)

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Target: DPH2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 3F7
Application*: E, IC, IF, WB
Datasheet SDS

Mouse Anti-DPH2 Recombinant Antibody (3A12) (CBMAB-D1553-YC)

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Target: DPH2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3A12
Application*: WB, P, F, IC, IF
Datasheet SDS

Mouse Anti-DPH2 Recombinant Antibody (2B12) (CBMAB-D1552-YC)

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Target: DPH2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 2B12
Application*: F, P, WB
Datasheet SDS

Mouse Anti-DPH2 Recombinant Antibody (1A12) (CBMAB-D1551-YC)

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Target: DPH2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1A12
Application*: P, WB
Datasheet SDS

Mouse Anti-DPH2 Recombinant Antibody (5B10) (V2LY-0425-LY828)

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Target: DPH2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat, Dog, Monkey
Clone: 5B10
Application*: F, IH, WB
Datasheet SDS

Mouse Anti-DPH2 Recombinant Antibody (4E7) (V2LY-0425-LY827)

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Target: DPH2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat
Clone: 4E7
Application*: WB, IP, IF
Datasheet SDS

Mouse Anti-DPH2 Recombinant Antibody (4D9) (V2LY-0425-LY826)

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Target: DPH2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Rat
Clone: 4D9
Application*: E, IF, WB
Datasheet SDS

Mouse Anti-DPH2 Recombinant Antibody (3F7) (V2LY-0425-LY825)

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Target: DPH2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 3F7
Application*: E, IF, WB
Datasheet SDS

Mouse Anti-DPH2 Recombinant Antibody (3A12) (V2LY-0425-LY824)

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Target: DPH2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Rat
Clone: 3A12
Application*: F, IH, WB, IF
Datasheet SDS

Mouse Anti-DPH2 Recombinant Antibody (2B12) (V2LY-0425-LY823)

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Target: DPH2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Rat
Clone: 2B12
Application*: F, IH, WB
Datasheet SDS

Mouse Anti-DPH2 Recombinant Antibody (1A12) (V2LY-0425-LY822)

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Target: DPH2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1A12
Application*: IH, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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