FMOD

Fibromodulin belongs to the family of small interstitial proteoglycans. The encoded protein possesses a central region containing leucine-rich repeats with 4 keratan sulfate chains, flanked by terminal domains containing disulphide bonds. Owing to the interaction with type I and type II collagen fibrils and in vitro inhibition of fibrillogenesis, the encoded protein may play a role in the assembly of extracellular matrix. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix. Sequence variations in this gene may be associated with the pathogenesis of high myopia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
Full Name
Fibromodulin
Function
Affects the rate of fibrils formation. May have a primary role in collagen fibrillogenesis (By similarity).
Biological Process
Collagen fibril organization Source: Ensembl
Transforming growth factor beta receptor complex assembly Source: ProtInc
Cellular Location
Extracellular matrix
PTM
Binds keratan sulfate chains.
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Anti-FMOD antibodies

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Target: FMOD
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: 770
Application*: ELISA, IHC, WB
Target: FMOD
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Mouse
Clone: CF171
Application*: ELISA, IHC
Target: FMOD
Host: Mouse
Specificity: Rat
Clone: CBXS-0019
Application*: WB, IC, P, C, E
Target: FMOD
Host: Mouse
Specificity: Human
Clone: CBXS-0018
Application*: WB, IC, P, C, E
Target: FMOD
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXF-1489
Application*: F
Target: FMOD
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXF-2274
Application*: E, IH, WB
Target: FMOD
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CBXF-2308
Application*: E, WB, IH, IR
Target: FMOD
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXF-0774
Application*: E, WB
Target: FMOD
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXF-2650
Application*: IS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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