GMEB1
This gene is a member of KDWK gene family. The product of this gene associates with GMEB2 protein, and the complex is essential for parvovirus DNA replication. Study of rat homolog implicates the role of this gene in modulation of transactivation by the glucocorticoid receptor bound to glucocorticoid response elements. Two alternative spliced transcript variants encoding different isoforms exist. [provided by RefSeq]
Full Name
GMEB1
Function
Trans-acting factor that binds to glucocorticoid modulatory elements (GME) present in the TAT (tyrosine aminotransferase) promoter and increases sensitivity to low concentrations of glucocorticoids. Binds also to the transferrin receptor promoter. Essential auxiliary factor for the replication of parvoviruses.
Biological Process
Regulation of transcription by RNA polymerase II Source: GO_Central
Cellular Location
Cytoplasm; Nucleus. May be also cytoplasmic.
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Anti-GMEB1 antibodies
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Target: GMEB1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBLG1-1358
Application*: WB, E, IF, P
Target: GMEB1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBLG1-1357
Application*: WB, E, IF, IP, P
Target: GMEB1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 1C1
Application*: WB
Target: GMEB1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat, Horse, Dog, Cattle
Clone: CBFYH-0399
Application*: WB, E, IF, IP, P
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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