Rabbit Anti-GMEB1 Recombinant Antibody (1C1) (CBMAB-0413-YC)

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Basic Information

Host Animal
Rabbit
Clone
1C1
Application
WB
Immunogen
Recombinant protein of human GMEB1.
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
Tris, BSA, glycerol
Preservative
Sodium azide
Concentration
1 mg/ml
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
GMEB1
Introduction
The GMEB1-GMEB2 complex is essential for parvovirus DNA replication. GMEB1 (glucocorticoid modulatory element binding protein 1) is a member of KDWK gene family which associates with GMEB2 protein. GMEB1's role may be to modulate the transactivation of the glucocorticoid receptor when it is bound to glucocorticoid response elements. Three alternative spliced transcript variants encoding different isoforms exist.
Entrez Gene ID
UniProt ID
Alternative Names
P96PIF; PIF96
Function
Trans-acting factor that binds to glucocorticoid modulatory elements (GME) present in the TAT (tyrosine aminotransferase) promoter and increases sensitivity to low concentrations of glucocorticoids. Binds also to the transferrin receptor promoter. Essential auxiliary factor for the replication of parvoviruses.
Biological Process
Regulation of transcription by RNA polymerase II Source: GO_Central
Cellular Location
Cytoplasm; Nucleus. May be also cytoplasmic.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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