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Mouse Anti-GMEB1 Antibody (1C1) (CBMAB-0413-YC)

Provided herein are mouse monoclonal antibodies against Human GMEB1. The antibody clone 1C1 can be used for immunoassay techniques, such as IP, WB and MA.
See all GMEB1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1C1
Antibody Isotype
IgG2b
Application
IP, WB, MA

Basic Information

Immunogen
Recombinant protein
Specificity
Human
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Supernatant
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
GMEB1
Introduction
The GMEB1-GMEB2 complex is essential for parvovirus DNA replication. GMEB1 (glucocorticoid modulatory element binding protein 1) is a member of KDWK gene family which associates with GMEB2 protein. GMEB1's role may be to modulate the transactivation of the glucocorticoid receptor when it is bound to glucocorticoid response elements. Three alternative spliced transcript variants encoding different isoforms exist.
Entrez Gene ID
10691
UniProt ID
Q9Y692
Alternative Names
P96PIF; PIF96
Function
Trans-acting factor that binds to glucocorticoid modulatory elements (GME) present in the TAT (tyrosine aminotransferase) promoter and increases sensitivity to low concentrations of glucocorticoids. Binds also to the transferrin receptor promoter. Essential auxiliary factor for the replication of parvoviruses.
Biological Process
Regulation of transcription by RNA polymerase II Source: GO_Central
Cellular Location
Cytoplasm; Nucleus. May be also cytoplasmic.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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