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Mouse Anti-GMEB1 Recombinant Antibody (CBLG1-1358) (CBMAB-G4005-LY)

This product is antibody recognizes GMEB1. The antibody CBLG1-1358 immunoassay techniques such as: ELISA, IF, IHC-P, WB.
See all GMEB1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBLG1-1358
Antibody Isotype
IgG2a
Application
ELISA, IF, IHC-P, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Concentration
0.5 mg/mL
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
GMEB1
Introduction
This gene encodes a member of KDWK gene family which associates with GMEB2 protein. The GMEB1-GMEB2 complex is essential for parvovirus DNA replication. Studies in rat for a similar gene suggest that this gene's role is to modulate the transactivation of the glucocorticoid receptor when it is bound to glucocorticoid response elements. Three alternative spliced transcript variants encoding different isoforms exist. [provided by RefSeq, Feb 2016]
Entrez Gene ID
UniProt ID
Alternative Names
Glucocorticoid Modulatory Element Binding Protein 1; Parvovirus Initiation Factor P96; DNA-Binding Protein P96PIF; PIF P96; Glucocorticoid Modulatory Element-Binding Protein 1; P96PIF; GMEB-1; PIF96;
Function
Trans-acting factor that binds to glucocorticoid modulatory elements (GME) present in the TAT (tyrosine aminotransferase) promoter and increases sensitivity to low concentrations of glucocorticoids. Binds also to the transferrin receptor promoter. Essential auxiliary factor for the replication of parvoviruses.
Biological Process
Regulation of transcription by RNA polymerase II Source: GO_Central
Cellular Location
Cytoplasm; Nucleus. May be also cytoplasmic.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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