IL25

The protein encoded by this gene is a cytokine that shares sequence similarity with interleukin 17. This cytokine can induce NF-kappaB activation, and stimulate the production of interleukin 8. Both this cytokine and interleukin 17B are ligands for the cytokine receptor IL17BR. Studies of a similar gene in mice suggest that this cytokine may be a pro-inflammatory cytokine favoring the Th2-type immune response. Alternative splicing results in multiple transcript variants.
Full Name
Interleukin 25
Function
Induces activation of NF-kappa-B and stimulates production of the proinflammatory chemokine IL-8. Proinflammatory cytokine favoring Th2-type immune responses.
Biological Process
Eosinophil differentiationIEA:Ensembl
Inflammatory response to antigenic stimulusIEA:Ensembl
Positive regulation of transcription by RNA polymerase IIIEA:Ensembl
Response to fungusIEA:Ensembl
Response to nematodeIEA:Ensembl
Cellular Location
Secreted
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Anti-IL25 antibodies

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Target: IL25
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Mouse, Human
Clone: CBYY-I1126
Application*: WB
Target: IL25
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: CBYY-I1075
Application*: WB
Target: IL25
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 8B1
Application*: F, WB
Target: IL25
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: CBYY-I0787
Application*: N
Target: IL25
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: 7H5
Application*: F
Target: IL25
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: 6D502
Application*: E, WB
Target: IL25
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: 68C1039.2
Application*: WB, P
Target: IL25
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5D10
Application*: E
Target: IL25
Host: Mouse
Antibody Isotype: IgG1
Specificity: Horse, Human, Mouse
Clone: 4H194
Application*: E, WB
Target: IL25
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: CBYY-I0448
Application*: WB, IF, F
Target: IL25
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-I0340
Application*: WB, F, MC
Target: IL25
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: CBYY-I0192
Application*: WB
Target: IL25
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: 207702
Application*: IS, MC, E
Target: IL25
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 182203
Application*: WB, IS, MC
More Infomation
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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