IL25

The protein encoded by this gene is a cytokine that shares sequence similarity with interleukin 17. This cytokine can induce NF-kappaB activation, and stimulate the production of interleukin 8. Both this cytokine and interleukin 17B are ligands for the cytokine receptor IL17BR. Studies of a similar gene in mice suggest that this cytokine may be a pro-inflammatory cytokine favoring the Th2-type immune response. Alternative splicing results in multiple transcript variants.

Full Name

Interleukin 25

Function

Induces activation of NF-kappa-B and stimulates production of the proinflammatory chemokine IL-8. Proinflammatory cytokine favoring Th2-type immune responses.

Biological Process

Eosinophil differentiationIEA:Ensembl
Inflammatory response to antigenic stimulusIEA:Ensembl
Positive regulation of transcription by RNA polymerase IIIEA:Ensembl
Response to fungusIEA:Ensembl
Response to nematodeIEA:Ensembl

Cellular Location

Secreted

Anti-IL25 antibodies

Mouse Anti-IL25 Recombinant Antibody (CBYY-I1126) (CBMAB-I2294-YY)

Datasheet

SDS

Target: IL25

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Mouse, Human

Clone: CBYY-I1126

Application*: WB

Rat Anti-IL25 Recombinant Antibody (CBYY-I1075) (CBMAB-I2243-YY)

Datasheet

SDS

Target: IL25

Host: Rat

Antibody Isotype: IgG2

Specificity: Mouse

Clone: CBYY-I1075

Application*: WB

Mouse Anti-IL25 Recombinant Antibody (8B1) (CBMAB-I1748-YY)

Datasheet

SDS

Target: IL25

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 8B1

Application*: F, WB

Rat Anti-IL25 Recombinant Antibody (CBYY-I0787) (CBMAB-I1738-YY)

Datasheet

SDS

Target: IL25

Host: Rat

Antibody Isotype: IgG2b

Specificity: Mouse

Clone: CBYY-I0787

Application*: N

Mouse Anti-IL25 Recombinant Antibody (7H5) (CBMAB-I1694-YY)

Datasheet

SDS

Target: IL25

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Mouse

Clone: 7H5

Application*: F

Mouse Anti-IL25 Recombinant Antibody (6D502) (CBMAB-I1563-YY)

Datasheet

SDS

Target: IL25

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Mouse

Clone: 6D502

Application*: E, WB

Mouse Anti-IL25 Recombinant Antibody (68C1039.2) (CBMAB-I1528-YY)

Datasheet

SDS

Target: IL25

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Mouse

Clone: 68C1039.2

Application*: WB, P

Mouse Anti-IL25 Recombinant Antibody (5D10) (CBMAB-I1434-YY)

Datasheet

SDS

Target: IL25

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 5D10

Application*: E

Mouse Anti-IL25 Recombinant Antibody (4H194) (CBMAB-I1359-YY)

Datasheet

SDS

Target: IL25

Host: Mouse

Antibody Isotype: IgG1

Specificity: Horse, Human, Mouse

Clone: 4H194

Application*: E, WB

Rat Anti-IL25 Recombinant Antibody (CBYY-I0448) (CBMAB-I1048-YY)

Datasheet

SDS

Target: IL25

Host: Rat

Antibody Isotype: IgG2

Specificity: Mouse

Clone: CBYY-I0448

Application*: WB, IF, F

Mouse Anti-IL25 Recombinant Antibody (CBYY-I0340) (CBMAB-I0882-YY)

Datasheet

SDS

Target: IL25

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYY-I0340

Application*: WB, F, MC

Rat Anti-IL25 Recombinant Antibody (CBYY-I0192) (CBMAB-I0521-YY)

Datasheet

SDS

Target: IL25

Host: Rat

Antibody Isotype: IgG2b

Specificity: Mouse

Clone: CBYY-I0192

Application*: WB

Rat Anti-IL25 Recombinant Antibody (207702) (CBMAB-I0520-YY)

Datasheet

SDS

Target: IL25

Host: Rat

Antibody Isotype: IgG2b

Specificity: Mouse

Clone: 207702

Application*: IS, MC, E

Mouse Anti-IL25 Recombinant Antibody (182203) (CBMAB-I0519-YY)

Datasheet

SDS

Target: IL25

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 182203

Application*: WB, IS, MC

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)