LHX9

This gene encodes a member of the LIM homeobox gene family of developmentally expressed transcription factors. The encoded protein contains a homeodomain and two cysteine-rich zinc-binding LIM domains involved in protein-protein interactions. The protein is highly similar to a mouse protein that causes gonadal agenesis when inactivated, suggesting a role in gonadal development. Alternative splicing results in multiple transcript variants. [provided by RefSeq]

LIM homeobox 9

Involved in gonadal development.

Cell population proliferationIEA:Ensembl
Dorsal spinal cord interneuron anterior axon guidanceISS:UniProtKB
Female gonad developmentIEA:Ensembl
Gonad morphogenesisIEA:Ensembl
Male gonad developmentIEA:Ensembl
Negative regulation of transcription, DNA-templatedISS:UniProtKB
Neuron differentiationManual Assertion Based On ExperimentIBA:GO_Central
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central

Nucleus