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Mouse Anti-Gro Recombinant Antibody (CBMAB-0482-LY)

This product is mouse antibody recognizes Gro of drosophila. The antibody immunoassay techniques such as: IF, WB, IP.
See all Gro antibodies

Summary

Host Animal
Mouse
Specificity
Common fruit fly
Antibody Isotype
IgG1
Application
IF, WB, IP

Basic Information

Immunogen
Partial protein
Specificity
Common fruit fly
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
groucho protein
Introduction
Transcriptional corepressor that regulates transcription when recruited to specific target DNA by hairy-related bHLH proteins. Maternally required for neurogenesis; in the segregation of the neuroectoderm. Directly or indirectly interacts with Notch and Delta.
Entrez Gene ID
43162
UniProt ID
P16371
Alternative Names
CG8384; Groucho; m9/m10; E(spl)gro; E(spl)m9/10
Function
Transcriptional corepressor that regulates transcription when recruited to specific target DNA by hairy-related bHLH proteins. Maternally required for neurogenesis; in the segregation of the neuroectoderm. Directly or indirectly interacts with Notch and Delta.
Biological Process
Cell differentiation Source: UniProtKB-KW
Epidermal growth factor receptor signaling pathway Source: FlyBase
Fibroblast growth factor receptor signaling pathway Source: FlyBase
Negative regulation of canonical Wnt signaling pathway Source: UniProtKB
Negative regulation of Toll signaling pathway Source: FlyBase
Negative regulation of transcription, DNA-templated Source: UniProtKB
Negative regulation of transcription by RNA polymerase II Source: FlyBase
Nervous system development Source: FlyBase
Regulation of transcription, DNA-templated Source: FlyBase
Sex determination, primary response to X:A ratio Source: FlyBase
Torso signaling pathway Source: FlyBase
Wnt signaling pathway Source: UniProtKB-KW
Cellular Location
Nucleus
PTM
Ubiquitinated by XIAP/BIRC4.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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