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Gro

Transcriptional corepressor that regulates transcription when recruited to specific target DNA by hairy-related bHLH proteins. Maternally required for neurogenesis; in the segregation of the neuroectoderm. Directly or indirectly interacts with Notch and Delta.

Full Name

groucho protein

Function

Transcriptional corepressor that regulates transcription when recruited to specific target DNA by hairy-related bHLH proteins. Maternally required for neurogenesis; in the segregation of the neuroectoderm. Directly or indirectly interacts with Notch and Delta.

Biological Process

Cell differentiation Source: UniProtKB-KW
Epidermal growth factor receptor signaling pathway Source: FlyBase
Fibroblast growth factor receptor signaling pathway Source: FlyBase
Negative regulation of canonical Wnt signaling pathway Source: UniProtKB
Negative regulation of Toll signaling pathway Source: FlyBase
Negative regulation of transcription, DNA-templated Source: UniProtKB
Negative regulation of transcription by RNA polymerase II Source: FlyBase
Nervous system development Source: FlyBase
Regulation of transcription, DNA-templated Source: FlyBase
Sex determination, primary response to X:A ratio Source: FlyBase
Torso signaling pathway Source: FlyBase
Wnt signaling pathway Source: UniProtKB-KW

Cellular Location

Nucleus

PTM

Ubiquitinated by XIAP/BIRC4.

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Anti-Gro antibodies

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Mouse Anti-Gro Monoclonal Antibody (1) (CBMAB-0482-LY)

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Target: Gro

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Common fruit fly

Clone: 1

Application*: IF, WB, IP

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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