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Gro

Transcriptional corepressor that regulates transcription when recruited to specific target DNA by hairy-related bHLH proteins. Maternally required for neurogenesis; in the segregation of the neuroectoderm. Directly or indirectly interacts with Notch and Delta.
Full Name
groucho protein
Function
Transcriptional corepressor that regulates transcription when recruited to specific target DNA by hairy-related bHLH proteins. Maternally required for neurogenesis; in the segregation of the neuroectoderm. Directly or indirectly interacts with Notch and Delta.
Biological Process
Cell differentiation Source: UniProtKB-KW
Epidermal growth factor receptor signaling pathway Source: FlyBase
Fibroblast growth factor receptor signaling pathway Source: FlyBase
Negative regulation of canonical Wnt signaling pathway Source: UniProtKB
Negative regulation of Toll signaling pathway Source: FlyBase
Negative regulation of transcription, DNA-templated Source: UniProtKB
Negative regulation of transcription by RNA polymerase II Source: FlyBase
Nervous system development Source: FlyBase
Regulation of transcription, DNA-templated Source: FlyBase
Sex determination, primary response to X:A ratio Source: FlyBase
Torso signaling pathway Source: FlyBase
Wnt signaling pathway Source: UniProtKB-KW
Cellular Location
Nucleus
PTM
Ubiquitinated by XIAP/BIRC4.

Anti-Gro antibodies

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Target: Gro
Host: Mouse
Antibody Isotype: IgG1
Specificity: Common fruit fly
Application*: IF, WB, IP
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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