LSP1

This gene encodes an intracellular F-actin binding protein. The protein is expressed in lymphocytes, neutrophils, macrophages, and endothelium and may regulate neutrophil motility, adhesion to fibrinogen matrix proteins, and transendothelial migration. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]
Full Name
lymphocyte-specific protein 1
Function
May play a role in mediating neutrophil activation and chemotaxis.
Biological Process
Cellular defense responseManual Assertion Based On ExperimentTAS:ProtInc
Cellular response to interleukin-7IEA:Ensembl
ChemotaxisIEA:Ensembl
Signal transductionIEA:InterPro
Cellular Location
Cell membrane
PTM
Phosphorylated by casein kinase II, protein kinase C and MAPKAPK2. Phosphorylation by PKC induces translocation from membrane to cytoplasm. Phosphorylation by MAPKAPK2 may regulate neutrophil chemotaxis (By similarity).
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Anti-LSP1 antibodies

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Rabbit Anti-LSP1 (Phosphorylated S204) Recombinant Antibody (PTM-CBMAB-0215LY)

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Target: LSP1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Application*: WB, P, PE
Datasheet SDS

Mouse Anti-LSP1 Recombinant Antibody (A943) (CBMAB-AP4315LY)

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Target: LSP1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: A943
Application*: IHC, IP, WB
Datasheet SDS

Mouse Anti-LSP1 Recombinant Antibody (1C4) (CBMAB-A5090-LY)

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Target: LSP1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1C4
Application*: WB, E
Datasheet SDS

Mouse Anti-LSP1 Recombinant Antibody (CBYCL-511) (CBMAB-L0412-YC)

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Target: LSP1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYCL-511
Application*: E, WB
Datasheet SDS

Mouse Anti-LSP1 Recombinant Antibody (CBYCL-510) (CBMAB-L0411-YC)

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Target: LSP1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYCL-510
Application*: WB, IH, E
Datasheet SDS

Mouse Anti-LSP1 Recombinant Antibody (CBYCL-509) (CBMAB-L0410-YC)

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Target: LSP1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYCL-509
Application*: IF, WB
Datasheet SDS

Mouse Anti-LSP1 Recombinant Antibody (TPD153) (CBMAB-L2238-YJ)

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Target: LSP1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: TPD153
Application*: WB, IH
Datasheet SDS

Mouse Anti-LSP1 Recombinant Antibody (CBYJL-2094) (CBMAB-L2237-YJ)

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Target: LSP1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJL-2094
Application*: WB, IP, IF, P
Datasheet SDS

Mouse Anti-LSP1 Recombinant Antibody (5E3) (CBMAB-L2234-YJ)

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Target: LSP1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 5E3
Application*: IF, WB
Datasheet SDS

Mouse Anti-LSP1 Recombinant Antibody (CBYJL-2091) (CBMAB-L2233-YJ)

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Target: LSP1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYJL-2091
Application*: E, WB
Datasheet SDS

Mouse Anti-LSP1 Recombinant Antibody (CBYJL-2090) (CBMAB-L2232-YJ)

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Target: LSP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJL-2090
Application*: WB, IF, IH
Datasheet SDS

Rabbit Anti-LSP1 (Phosphorylated S190) Recombinant Antibody (PTM-CBMAB-0945LY)

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Target: LSP1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Application*: E, WB, IH
Datasheet SDS

Rabbit Anti-LSP1 (Phosphorylated S252) Recombinant Antibody (PTM-CBMAB-0217LY)

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Target: LSP1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Application*: WB, P, PE
Datasheet SDS
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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