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LSR

LSR probable play a role in the clearance of triglyceride-rich lipoprotein from blood. Binds chylomicrons, LDL and VLDL in presence of free fatty acids and allows their subsequent uptake in the cells.
Full Name
LSR
Function
Probable role in the clearance of triglyceride-rich lipoprotein from blood. Binds chylomicrons, LDL and VLDL in presence of free fatty acids and allows their subsequent uptake in the cells (By similarity).
Maintains epithelial barrier function by recruiting MARVELD2/tricellulin to tricellular tight junctions (By similarity).
Biological Process
Epithelial structure maintenanceISS:UniProtKB
Establishment of blood-brain barrierISS:ARUK-UCL
Establishment of skin barrierISS:ARUK-UCL
Liver developmentISS:HGNC
Maintenance of blood-brain barrier1 PublicationNAS:ARUK-UCL
Protein localization to tricellular tight junctionISS:ARUK-UCL
Tricellular tight junction assemblyISS:ARUK-UCL
Cellular Location
Cell membrane
Cell junction, tight junction
Located at tricellular contacts.
Topology
Extracellular: 1-259
Helical: 260-280
Cytoplasmic: 281-649
PTM
Phosphorylation at Ser-365 by MAPK8/JNK1 and MAPK9/JNK2 may be required for exclusive localization at tricellular tight junstions.
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Anti-LSR antibodies

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Mouse Anti-LSR Recombinant Antibody (CBYJL-2095) (CBMAB-L2239-YJ)

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Target: LSR
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJL-2095
Application*: E, IC, IH, WB
Datasheet SDS

Mouse Anti-LSR Recombinant Antibody (A944) (CBMAB-AP4295LY)

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Target: LSR
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: A944
Application*: ICC, IHC, IP, WB
Datasheet SDS

Rabbit Anti-LSR Recombinant Antibody (CBYCL-515) (CBMAB-L0416-YC)

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Target: LSR
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Monkey
Clone: CBYCL-515
Application*: WB, IP, P
Datasheet SDS

Mouse Anti-LSR Recombinant Antibody (CBYCL-514) (CBMAB-L0415-YC)

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Target: LSR
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYCL-514
Application*: E, WB
Datasheet SDS

Mouse Anti-LSR Recombinant Antibody (CBYCL-513) (CBMAB-L0414-YC)

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Target: LSR
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYCL-513
Application*: IC, C, P, E, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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