METTL21A

METTL21A (Methyltransferase Like 21A) is a Protein Coding gene. Among its related pathways are Metabolism of proteins and Protein methylation. Gene Ontology (GO) annotations related to this gene include methyltransferase activity and Hsp70 protein binding. An important paralog of this gene is EEF1AKMT3.
Full Name
METTL21A
Function
S-adenosyl-L-methionine-dependent methyltransferase that mediates N3-methylcytidine modification of residue 32 of the tRNA anticodon loop of tRNA(Thr)(UGU) and tRNA(Arg)(CCU) (PubMed:28655767, PubMed:34268557).

N3-methylcytidine methylation by METTL2A requires the N6-threonylcarbamoylation of tRNA (t6A37) by the EKC/KEOPS complex as prerequisite (PubMed:34268557).
Biological Process
tRNA methylation Source: UniProtKB
Cellular Location
Cytoplasm
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Anti-METTL21A antibodies

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Target: METTL21A
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYM-2125
Application*: WB
Target: METTL21A
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYH-2653
Application*: F, P, WB
Target: METTL21A
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 2D2
Application*: IP, M
Target: METTL21A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-3633
Application*: WB
Target: METTL21A
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXF-3608
Application*: WB
Target: METTL21A
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXF-2525
Application*: WB, IF
Target: METTL21A
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 2G7
Application*: WB, F, IH, P
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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