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METTL21A

METTL21A (Methyltransferase Like 21A) is a Protein Coding gene. Among its related pathways are Metabolism of proteins and Protein methylation. Gene Ontology (GO) annotations related to this gene include methyltransferase activity and Hsp70 protein binding. An important paralog of this gene is EEF1AKMT3.
Full Name
METTL21A
Function
S-adenosyl-L-methionine-dependent methyltransferase that mediates N3-methylcytidine modification of residue 32 of the tRNA anticodon loop of tRNA(Thr)(UGU) and tRNA(Arg)(CCU) (PubMed:28655767, PubMed:34268557).

N3-methylcytidine methylation by METTL2A requires the N6-threonylcarbamoylation of tRNA (t6A37) by the EKC/KEOPS complex as prerequisite (PubMed:34268557).
Biological Process
tRNA methylation Source: UniProtKB
Cellular Location
Cytoplasm

Anti-METTL21A antibodies

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Target: METTL21A
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYM-2125
Application*: WB
Target: METTL21A
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYH-2653
Application*: F, P, WB
Target: METTL21A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-3633
Application*: WB
Target: METTL21A
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXF-3608
Application*: WB
Target: METTL21A
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXF-2525
Application*: WB, IF
Target: METTL21A
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 2G7
Application*: WB, F, IH, P
Target: METTL21A
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 2D2
Application*: IP, M
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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