SUSD2

SUSD2 (Sushi Domain Containing 2) is a Protein Coding gene. Diseases associated with SUSD2 include Breast Cancer. Gene Ontology (GO) annotations related to this gene include scavenger receptor activity and polysaccharide binding. An important paralog of this gene is MUC4.May be a cytokine receptor for C10ORF99. May be a tumor suppressor; together with C10ORF99 has a growth inhibitory effect on colon cancer cells which includes G1 cell cycle arrest (PubMed:25351403). May play a role in breast tumorigenesis (PubMed:23131994).
Full Name
Sushi Domain Containing 2
Function
May be a cytokine receptor for GPR15LG. May be a tumor suppressor; together with GPR15LG has a growth inhibitory effect on colon cancer cells which includes G1 cell cycle arrest (PubMed:25351403).
May play a role in breast tumorigenesis (PubMed:23131994).
Biological Process
Biological Process negative regulation of cell cycle G1/S phase transitionManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process negative regulation of cell divisionManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Cell membrane
SUSD2 and LGALS1 co-localized in very specific, punctate regions along the cell membrane of breast cancer cells.
Topology
Extracellular: 28-785
Helical: 786-806
Cytoplasmic: 807-822
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Anti-SUSD2 antibodies

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Human Anti-SUSD2 Recombinant Antibody (CBXS-3571) (CBMAB-S0386-CQ)

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Target: SUSD2
Host: Human
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-3571
Application*: F
Datasheet SDS

Rabbit Anti-SUSD2 Recombinant Antibody (CBXS-1672) (CBMAB-S0095-CQ)

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Target: SUSD2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Rat
Clone: CBXS-1672
Application*: F
Datasheet SDS

Mouse Anti-SUSD2 Recombinant Antibody (CBXS-1989) (CBMAB-S4758-CQ)

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Target: SUSD2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXS-1989
Application*: WB, IH
Datasheet SDS

Rabbit Anti-SUSD2 Recombinant Antibody (CBXS-1620) (CBMAB-S4469-CQ)

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Target: SUSD2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBXS-1620
Application*: WB
Datasheet SDS

Mouse Anti-SUSD2 Recombinant Antibody (W5C5) (CBMAB-S0379-CQ)

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Target: SUSD2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: W5C5
Application*: F
Datasheet SDS

Rabbit Anti-SUSD2 Recombinant Antibody (CBXS-3677) (CBMAB-S0215-CQ)

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Target: SUSD2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBXS-3677
Application*: WB, F, IH, MC
Datasheet SDS

Rabbit Anti-SUSD2 Recombinant Antibody (CBXS-3676) (CBMAB-S0214-CQ)

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Target: SUSD2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Rat
Clone: CBXS-3676
Application*: WB, F, MC
Datasheet SDS

Mouse Anti-SUSD2 Recombinant Antibody (CBXS-1990) (CBMAB-S0156-CQ)

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Target: SUSD2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXS-1990
Application*: F
Datasheet SDS

Rabbit Anti-SUSD2 Recombinant Antibody (CBXS-1671) (CBMAB-S0094-CQ)

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Target: SUSD2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBXS-1671
Application*: F
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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