Rabbit Anti-SUSD2 Recombinant Antibody (CBXS-3676) (V2LY-0726-LY262)

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Basic Information

Host Animal
Rabbit
Clone
CBXS-3676
Application
WB, FC, MC
Immunogen
Partial recombinant human SUSD2 protein (amino acids 1-785).
Host Species
Rabbit
Specificity
Human, Rat
Antibody Isotype
IgG
Clonality
Monoclonal

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
None
Concentration
1 mg/ml
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
Sushi Domain Containing 2
Entrez Gene ID
Human56241
Rat294335
UniProt ID
HumanQ9UGT4
RatB5DEX6
Function
May be a cytokine receptor for GPR15LG. May be a tumor suppressor; together with GPR15LG has a growth inhibitory effect on colon cancer cells which includes G1 cell cycle arrest (PubMed:25351403).
May play a role in breast tumorigenesis (PubMed:23131994).
Biological Process
Biological Process negative regulation of cell cycle G1/S phase transitionManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process negative regulation of cell divisionManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Cell membrane
SUSD2 and LGALS1 co-localized in very specific, punctate regions along the cell membrane of breast cancer cells.
Topology
Extracellular: 28-785
Helical: 786-806
Cytoplasmic: 807-822
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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