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TRIM9

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Its function has not been identified. Alternate splicing of this gene generates two transcript variants encoding different isoforms. [provided by RefSeq]

Full Name

tripartite motif-containing 9

Function

E3 ubiquitin-protein ligase which ubiquitinates itself in cooperation with an E2 enzyme UBE2D2/UBC4 and serves as a targeting signal for proteasomal degradation. May play a role in regulation of neuronal functions and may also participate in the formation or breakdown of abnormal inclusions in neurodegenerative disorders. May act as a regulator of synaptic vesicle exocytosis by controlling the availability of SNAP25 for the SNARE complex formation.

Biological Process

Biological Process proteasome-mediated ubiquitin-dependent protein catabolic process Source:UniProtKB1 Publication

Cellular Location

Cytoplasm
Cell projection, dendrite
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle
Synapse
Cytoplasm, cytoskeleton
Enriched at synaptic terminals where it exists in a soluble form and a synaptic vesicle-associated form. Associated with the cytoskeleton (By similarity).
Found in proximal dendrites of pyramidal neurons in the cerebral cortex and hippocampus, and Purkinje cells in the cerebellum (PubMed:20085810).

PTM

Auto-ubiquitinated. Poly-ubiquitinated in cultured cells, whereas it is monoubiquitinated in vitro.

Anti-TRIM9 antibodies

Mouse Anti-TRIM9 Recombinant Antibody (CBXS-4060) (CBMAB-S1319-CQ)

SDS

Target: TRIM9

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBXS-4060

Application*: F, IF, WB

Mouse Anti-TRIM9 Recombinant Antibody (CBXS-4151) (CBMAB-S1404-CQ)

SDS

Target: TRIM9

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBXS-4151

Application*: F, IF, WB

Mouse Anti-TRIM9 Recombinant Antibody (CBXS-4326) (CBMAB-S1571-CQ)

SDS

Target: TRIM9

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXS-4326

Application*: F, WB

Mouse Anti-TRIM9 Recombinant Antibody (1F12) (CBMAB-A9539-LY)

SDS

Target: TRIM9

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: 1F12

Application*: WB, E

Mouse Anti-TRIM9 Recombinant Antibody (CBYJT-4834) (CBMAB-T4377-YJ)

SDS

Target: TRIM9

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBYJT-4834

Application*: WB, IF, F

Mouse Anti-TRIM9 Recombinant Antibody (CBYJT-4835) (CBMAB-T4378-YJ)

SDS

Target: TRIM9

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: CBYJT-4835

Application*: E, WB

Mouse Anti-TRIM9 Recombinant Antibody (CBYJT-4836) (CBMAB-T4379-YJ)

SDS

Target: TRIM9

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBYJT-4836

Application*: WB, IF, F

Mouse Anti-TRIM9 Recombinant Antibody (CBYJT-4837) (CBMAB-T4380-YJ)

SDS

Target: TRIM9

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYJT-4837

Application*: WB, F

Mouse Anti-TRIM9 Recombinant Antibody (CBYJT-4838) (CBMAB-T4381-YJ)

SDS

Target: TRIM9

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBYJT-4838

Application*: WB, F

Mouse Anti-TRIM9 Recombinant Antibody (CBYJT-4839) (CBMAB-T4382-YJ)

SDS

Target: TRIM9

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBYJT-4839

Application*: WB, IF

Mouse Anti-TRIM9 Recombinant Antibody (CBYJT-4840) (CBMAB-T4383-YJ)

SDS

Target: TRIM9

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYJT-4840

Application*: WB

Mouse Anti-TRIM9 Recombinant Antibody (CBYJT-4841) (CBMAB-T4384-YJ)

SDS

Target: TRIM9

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBYJT-4841

Application*: IF, F

Mouse Anti-TRIM9 Recombinant Antibody (CBYJT-4842) (CBMAB-T4385-YJ)

SDS

Target: TRIM9

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBYJT-4842

Application*: WB, IF, F

Mouse Anti-TRIM9 Recombinant Antibody (CBYJT-4843) (CBMAB-T4386-YJ)

SDS

Target: TRIM9

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYJT-4843

Application*: WB

Mouse Anti-TRIM9 Recombinant Antibody (CBYJT-4844) (CBMAB-T4387-YJ)

SDS

Target: TRIM9

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human, Monkey

Clone: CBYJT-4844

Application*: WB, F, IC, IF

Mouse Anti-TRIM9 Recombinant Antibody (CBYJT-4845) (CBMAB-T4388-YJ)

SDS

Target: TRIM9

Host: Mouse

Antibody Isotype: IgG

Specificity: Human, Rat, Mouse

Clone: CBYJT-4845

Application*: WB, IP, IF, E

Mouse Anti-TRIM9 Recombinant Antibody (CBYJT-4846) (CBMAB-T4389-YJ)

SDS

Target: TRIM9

Host: Mouse

Antibody Isotype: IgG

Specificity: Human, Rat, Mouse

Clone: CBYJT-4846

Application*: WB, IP, IF, E

Mouse Anti-TRIM9 Recombinant Antibody (CBXS-4367) (CBMAB-S0239-CQ)

SDS

Target: TRIM9

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBXS-4367

Application*: F, WB

Mouse Anti-TRIM9 (AA 284-669) Recombinant Antibody (CBXS-4398) (CBMAB-S1640-CQ)

SDS

Target: TRIM9

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBXS-4398

Application*: IF, WB

Mouse Anti-TRIM9 Recombinant Antibody (CBXS-4501) (CBMAB-S1742-CQ)

SDS

Target: TRIM9

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBXS-4501

Application*: F, IF, WB

Mouse Anti-TRIM9 (AA 284-669) Recombinant Antibody (CBXS-4509) (CBMAB-S1750-CQ)

SDS

Target: TRIM9

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXS-4509

Application*: WB

Mouse Anti-TRIM9 Recombinant Antibody (CBXS-4647) (CBMAB-S1886-CQ)

SDS

Target: TRIM9

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBXS-4647

Application*: F, IF

Mouse Anti-TRIM9 Recombinant Antibody (CBXS-4823) (CBMAB-S2047-CQ)

SDS

Target: TRIM9

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBXS-4823

Application*: F, IF, WB

Mouse Anti-TRIM9 Recombinant Antibody (CBXS-5180) (CBMAB-S2398-CQ)

SDS

Target: TRIM9

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXS-5180

Application*: WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)

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