TRIM9

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Its function has not been identified. Alternate splicing of this gene generates two transcript variants encoding different isoforms. [provided by RefSeq]
Full Name
tripartite motif-containing 9
Function
E3 ubiquitin-protein ligase which ubiquitinates itself in cooperation with an E2 enzyme UBE2D2/UBC4 and serves as a targeting signal for proteasomal degradation. May play a role in regulation of neuronal functions and may also participate in the formation or breakdown of abnormal inclusions in neurodegenerative disorders. May act as a regulator of synaptic vesicle exocytosis by controlling the availability of SNAP25 for the SNARE complex formation.
Biological Process
Biological Process proteasome-mediated ubiquitin-dependent protein catabolic process Source:UniProtKB1 Publication
Cellular Location
Cytoplasm
Cell projection, dendrite
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle
Synapse
Cytoplasm, cytoskeleton
Enriched at synaptic terminals where it exists in a soluble form and a synaptic vesicle-associated form. Associated with the cytoskeleton (By similarity).
Found in proximal dendrites of pyramidal neurons in the cerebral cortex and hippocampus, and Purkinje cells in the cerebellum (PubMed:20085810).
PTM
Auto-ubiquitinated. Poly-ubiquitinated in cultured cells, whereas it is monoubiquitinated in vitro.
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Anti-TRIM9 antibodies

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Target: TRIM9
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 1F12
Application*: WB, E
Target: TRIM9
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5180
Application*: WB
Target: TRIM9
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXS-4823
Application*: F, IF, WB
Target: TRIM9
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXS-4647
Application*: F, IF
Target: TRIM9
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-4509
Application*: WB
Target: TRIM9
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXS-4501
Application*: F, IF, WB
Target: TRIM9
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXS-4398
Application*: IF, WB
Target: TRIM9
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-4326
Application*: F, WB
Target: TRIM9
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXS-4151
Application*: F, IF, WB
Target: TRIM9
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXS-4060
Application*: F, IF, WB
Target: TRIM9
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXS-4367
Application*: F, WB
Target: TRIM9
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Rat, Mouse
Clone: CBYJT-4846
Application*: WB, IP, IF, E
Target: TRIM9
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Rat, Mouse
Clone: CBYJT-4845
Application*: WB, IP, IF, E
Target: TRIM9
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Monkey
Clone: CBYJT-4844
Application*: WB, F, IC, IF
Target: TRIM9
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-4843
Application*: WB
Target: TRIM9
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYJT-4842
Application*: WB, IF, F
Target: TRIM9
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYJT-4841
Application*: IF, F
Target: TRIM9
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-4840
Application*: WB
Target: TRIM9
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYJT-4839
Application*: WB, IF
Target: TRIM9
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYJT-4838
Application*: WB, F
Target: TRIM9
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-4837
Application*: WB, F
Target: TRIM9
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYJT-4836
Application*: WB, IF, F
Target: TRIM9
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBYJT-4835
Application*: E, WB
Target: TRIM9
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYJT-4834
Application*: WB, IF, F
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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