WFIKKN2
The WFIKKN1 protein contains a WAP domain, follistatin domain, immunoglobulin domain, two tandem Kunitz domains, and an NTR domain. This gene encodes a WFIKKN1-related protein which has the same domain organization as the WFIKKN1 protein. The WAP-type, follistatin type, Kunitz-type, and NTR-type protease inhibitory domains may control the action of multiple types of proteases. [provided by RefSeq, Jul 2008]
Full Name
WAP, Follistatin/Kazal, Immunoglobulin, Kunitz And Netrin Domain Containing 2
Function
Protease-inhibitor that contains multiple distinct protease inhibitor domains. Probably has serine protease- and metalloprotease-inhibitor activity. Inhibits the biological activity of mature myostatin, but not activin (By similarity).
Biological Process
Biological Process muscle cell development Source:Ensembl
Biological Process negative regulation of DNA binding Source:Ensembl
Biological Process negative regulation of protein binding Source:Ensembl
Biological Process negative regulation of transforming growth factor beta receptor signaling pathway Source:UniProtKB1 Publication
Biological Process roof of mouth development Source:Ensembl
Biological Process skeletal system development Source:Ensembl
Biological Process transforming growth factor beta receptor signaling pathway Source:UniProtKBBy Similarity
Biological Process negative regulation of DNA binding Source:Ensembl
Biological Process negative regulation of protein binding Source:Ensembl
Biological Process negative regulation of transforming growth factor beta receptor signaling pathway Source:UniProtKB1 Publication
Biological Process roof of mouth development Source:Ensembl
Biological Process skeletal system development Source:Ensembl
Biological Process transforming growth factor beta receptor signaling pathway Source:UniProtKBBy Similarity
Cellular Location
Secreted
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Anti-WFIKKN2 antibodies
+ Filters
Target: WFIKKN2
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-576
Tag: His Tag
Target: WFIKKN2
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: 17V26
Application*: E
Target: WFIKKN2
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: 14L462
Application*: E
Target: WFIKKN2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 288518
Application*: WB
Target: WFIKKN2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 288504
Application*: EC
Target: WFIKKN2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBFYH-2841
Application*: WB, IP
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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