WFIKKN2

The WFIKKN1 protein contains a WAP domain, follistatin domain, immunoglobulin domain, two tandem Kunitz domains, and an NTR domain. This gene encodes a WFIKKN1-related protein which has the same domain organization as the WFIKKN1 protein. The WAP-type, follistatin type, Kunitz-type, and NTR-type protease inhibitory domains may control the action of multiple types of proteases. [provided by RefSeq, Jul 2008]
Full Name
WAP, Follistatin/Kazal, Immunoglobulin, Kunitz And Netrin Domain Containing 2
Function
Protease-inhibitor that contains multiple distinct protease inhibitor domains. Probably has serine protease- and metalloprotease-inhibitor activity. Inhibits the biological activity of mature myostatin, but not activin (By similarity).
Biological Process
Biological Process muscle cell development Source:Ensembl
Biological Process negative regulation of DNA binding Source:Ensembl
Biological Process negative regulation of protein binding Source:Ensembl
Biological Process negative regulation of transforming growth factor beta receptor signaling pathway Source:UniProtKB1 Publication
Biological Process roof of mouth development Source:Ensembl
Biological Process skeletal system development Source:Ensembl
Biological Process transforming growth factor beta receptor signaling pathway Source:UniProtKBBy Similarity
Cellular Location
Secreted
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Anti-WFIKKN2 antibodies

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Target: WFIKKN2
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: 17V26
Application*: E
Target: WFIKKN2
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: 14L462
Application*: E
Target: WFIKKN2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 288518
Application*: WB
Target: WFIKKN2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 288504
Application*: EC
Target: WFIKKN2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBFYH-2841
Application*: WB, IP
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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