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WFIKKN2

The WFIKKN1 protein contains a WAP domain, follistatin domain, immunoglobulin domain, two tandem Kunitz domains, and an NTR domain. This gene encodes a WFIKKN1-related protein which has the same domain organization as the WFIKKN1 protein. The WAP-type, follistatin type, Kunitz-type, and NTR-type protease inhibitory domains may control the action of multiple types of proteases. [provided by RefSeq, Jul 2008]

Full Name

WAP, Follistatin/Kazal, Immunoglobulin, Kunitz And Netrin Domain Containing 2

Function

Protease-inhibitor that contains multiple distinct protease inhibitor domains. Probably has serine protease- and metalloprotease-inhibitor activity. Inhibits the biological activity of mature myostatin, but not activin (By similarity).

Biological Process

Biological Process muscle cell development Source:Ensembl
Biological Process negative regulation of DNA binding Source:Ensembl
Biological Process negative regulation of protein binding Source:Ensembl
Biological Process negative regulation of transforming growth factor beta receptor signaling pathway Source:UniProtKB1 Publication
Biological Process roof of mouth development Source:Ensembl
Biological Process skeletal system development Source:Ensembl
Biological Process transforming growth factor beta receptor signaling pathway Source:UniProtKBBy Similarity

Cellular Location

Secreted

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Anti-WFIKKN2 antibodies

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Mouse Anti-WFIKKN2 Recombinant Antibody (17V26) (CBMAB-G6686-LY)

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Target: WFIKKN2

Host: Mouse

Antibody Isotype: IgG2

Specificity: Human

Clone: 17V26

Application*: E

Mouse Anti-WFIKKN2 Recombinant Antibody (14L462) (CBMAB-G6685-LY)

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Target: WFIKKN2

Host: Mouse

Antibody Isotype: IgG2

Specificity: Human

Clone: 14L462

Application*: E

Mouse Anti-WFIKKN2 Recombinant Antibody (288518) (CBMAB-G1230-LY)

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Target: WFIKKN2

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: 288518

Application*: WB

Mouse Anti-WFIKKN2 Recombinant Antibody (288504) (CBMAB-G1229-LY)

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Target: WFIKKN2

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: 288504

Application*: EC

Mouse Anti-WFIKKN2 Recombinant Antibody (CBFYH-2841) (CBMAB-H3916-FY)

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Target: WFIKKN2

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBFYH-2841

Application*: WB, IP

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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