Mouse Anti-BTN3A2 Recombinant Antibody (CBFYC-0586) (CBMAB-C0640-FY)

Name: Mouse Anti-BTN3A2 Recombinant Antibody (CBFYC-0586)
SKU: CBMAB-C0640-FY
Rating: 5 (1 reviews)

See all BTN3A2 antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBFYC-0586

Application

WB, IH, IF

Immunogen

Full length human recombinant protein of human BTN3A2 produced in HEK293T cell.

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG2a, κ

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Application	Note
WB	1:2,000
IF(ICC)	1:50
IHC	1:100

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.3, 1% BSA, 50% glycerol

Preservative

0.02% sodium azide

Concentration

1 mg/ml

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

BUTYROPHILIN SUBFAMILY 3 MEMBER A2

Introduction

This gene encodes a member of the immunoglobulin superfamily, which resides in the juxta-telomeric region of the major histocompatability class 1 locus and is clustered with the other family members on chromosome 6. The encoded protein may be involved in the adaptive immune response. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Entrez Gene ID

11118

UniProt ID

P78410

Alternative Names

BTF4; BT3.2; CD277; BTN3.2

Function

Plays a role in T-cell responses in the adaptive immune response. Inhibits the release of IFNG from activated T-cells.

Biological Process

Adaptive immune response Source: Reactome
Positive regulation of interferon-gamma production Source: UniProtKB
Regulation of cytokine production Source: GO_Central
T cell mediated immunity Source: UniProtKB
T cell receptor signaling pathway Source: GO_Central

Cellular Location

Cell membrane

Topology

Extracellular: 30-248 aa
Helical: 249-269 aa
Cytoplasmic: 270-334 aa

PTM

N-glycosylated.

Zhou, H., & Lin, Y. (2021). BTN3A2 Expression Is Connected With Favorable Prognosis and High Infiltrating Immune in Lung Adenocarcinoma.

Cai, P., Lu, Z., Wu, J., Qin, X., Wang, Z., Zhang, Z., ... & Zhao, J. (2020). BTN3A2 serves as a prognostic marker and favors immune infiltration in triple‐negative breast cancer. Journal of cellular biochemistry, 121(3), 2643-2654.

Zhu, M., Yan, C., Ren, C., Huang, X., Zhu, X., Gu, H., ... & Jin, G. (2017). Exome array analysis identifies variants in SPOCD1 and BTN3A2 that affect risk for gastric cancer. Gastroenterology, 152(8), 2011-2021.

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Mouse Anti-BTN3A2 Recombinant Antibody (CBFYC-0586)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry