BTN3A2
This gene encodes a member of the immunoglobulin superfamily, which resides in the juxta-telomeric region of the major histocompatability class 1 locus and is clustered with the other family members on chromosome 6. The encoded protein may be involved in the adaptive immune response. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Full Name
BUTYROPHILIN SUBFAMILY 3 MEMBER A2
Function
Plays a role in T-cell responses in the adaptive immune response. Inhibits the release of IFNG from activated T-cells.
Biological Process
Adaptive immune response Source: Reactome
Positive regulation of interferon-gamma production Source: UniProtKB
Regulation of cytokine production Source: GO_Central
T cell mediated immunity Source: UniProtKB
T cell receptor signaling pathway Source: GO_Central
Positive regulation of interferon-gamma production Source: UniProtKB
Regulation of cytokine production Source: GO_Central
T cell mediated immunity Source: UniProtKB
T cell receptor signaling pathway Source: GO_Central
Cellular Location
Cell membrane
Topology
Extracellular: 30-248 aa
Helical: 249-269 aa
Cytoplasmic: 270-334 aa
Helical: 249-269 aa
Cytoplasmic: 270-334 aa
PTM
N-glycosylated.
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Anti-BTN3A2 antibodies
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Target: BTN3A2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYC-0586
Application*: WB, IH, IF
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot

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