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Mouse Anti-CLEC9A Recombinant Antibody (8F9) (CBMAB-C9195-LY)

This product is antibody recognizes CLEC9A. The antibody 8F9 immunoassay techniques such as: FC.
See all CLEC9A antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
8F9
Antibody Isotype
IgG2a, κ
Application
FC

Basic Information

Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
0.2% (w/v) BSA
Preservative
0.09% sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
C-Type Lectin Domain Containing 9A
Introduction
CLEC9A is a group V C-type lectin-like receptor (CTLR) that functions as an activation receptor and is expressed on myeloid lineage cells (Huysamen et al., 2008 [PubMed 18408006]).[supplied by OMIM, Aug 2008]
Entrez Gene ID
283420
UniProt ID
Q6UXN8
Alternative Names
C-Type Lectin Domain Containing 9A; C-Type Lectin Domain Family 9 Member A; C-Type Lectin Domain Family 9, Member A; HEEE9341; UNQ9341; DNGR-1; CD370; DNGR1;
Function
Functions as an endocytic receptor on a small subset of myeloid cells specialized for the uptake and processing of material from dead cells. Recognizes filamentous form of actin in association with particular actin-binding domains of cytoskeletal proteins, including spectrin, exposed when cell membranes are damaged, and mediate the cross-presentation of dead-cell associated antigens in a Syk-dependent manner.
Biological Process
Positive regulation of cytokine production Source: UniProtKB
Receptor-mediated endocytosis Source: UniProtKB
Cellular Location
Membrane
Topology
Cytoplasmic: 1-35
Helical: 36-56
Extracellular: 57-241
PTM
N-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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