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Mouse Anti-COG7 Recombinant Antibody (CBXC-0502) (V2LY-1206-LY577)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXC-0502
Antibody Isotype
IgG2b, κ
Application
WB, IP, IF, ELISA, IHC-P

Basic Information

Immunogen
Amino acids 1-300 mapping at the N-terminus of COG7 of human.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
WB1:100-1:1,000
IP1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)
IF(ICC)1:50-1:500
ELISA1:100-1:1,000
IHC-P1:50-1:500

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
0.1% gelatin
Preservative
<0.1% sodium azide
Concentration
0.2 mg/ml
Purity
>95% as determined by analysis by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
component of oligomeric golgi complex 7
Entrez Gene ID
91949
UniProt ID
P83436
Function
Required for normal Golgi function.
Biological Process
Endoplasmic reticulum to Golgi vesicle-mediated transport Source: Reactome
Golgi organization Source: GO_Central
Intracellular protein transport Source: UniProtKB
Protein glycosylation Source: UniProtKB
Protein localization to Golgi apparatus Source: UniProtKB
Protein localization to organelle Source: UniProtKB
Protein stabilization Source: UniProtKB
Retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum Source: UniProtKB
Cellular Location
Golgi apparatus membrane
Involvement in disease
Congenital disorder of glycosylation 2E (CDG2E):
A multisystem disorder caused by a defect in glycoprotein biosynthesis and characterized by under-glycosylated serum glycoproteins. Congenital disorders of glycosylation result in a wide variety of clinical features, such as defects in the nervous system development, psychomotor retardation, dysmorphic features, hypotonia, coagulation disorders, and immunodeficiency. The broad spectrum of features reflects the critical role of N-glycoproteins during embryonic development, differentiation, and maintenance of cell functions.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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