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Rabbit Anti-EPN2 Recombinant Antibody (EG1117) (CBMAB-EN1327-LY)

The product is antibody recognizes EPN2. The antibody EG1117 immunoassay techniques such as: WB: 1:500~1:1000 ELISA: 1:20000.
See all EPN2 antibodies

Summary

Host Animal
Rabbit
Specificity
Human, Mouse, Rat
Clone
EG1117
Antibody Isotype
IgG
Application
WB: 1:500~1:1000 ELISA: 1:20000

Basic Information

Immunogen
The antibody was produced against synthesized peptide derived from internal of human EPN2.
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Epsin 2
Introduction
This gene encodes a protein which interacts with clathrin and adaptor-related protein complex 2, alpha 1 subunit. The protein is found in a brain-derived clathrin-coated vesicle fraction and localizes to the peri-Golgi region and the cell periphery. The protein is thought to be involved in clathrin-mediated endocytosis. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Entrez Gene ID
Human22905
Mouse13855
Rat60443
UniProt ID
HumanO95208
MouseQ8CHU3
RatQ9Z1Z3
Alternative Names
Epsin 2; EPS-15-Interacting Protein 2; Eps15 Binding Protein; KIAA1065; Epsin-2; EHB21;
Research Area
Plays a role in the formation of clathrin-coated invaginations and endocytosis.
Biological Process
Endocytosis Source: GO_Central
Negative regulation of sprouting angiogenesis Source: BHF-UCL
Negative regulation of vascular endothelial growth factor receptor signaling pathway Source: BHF-UCL
Positive regulation of Notch signaling pathway Source: BHF-UCL
Cellular Location
Cytoplasm; Clathrin-coated vesicle. In punctate structures throughout the cell, associated with clathrin-coated vesicles, and particularly concentrated in the region of the Golgi complex.
PTM
Ubiquitinated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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