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Mouse Anti-EPN2 Recombinant Antibody (CBFYE-1054) (CBMAB-E1574-FY)

This product is mouse antibody that recognizes EPN2. The antibody CBFYE-1054 can be used for immunoassay techniques such as: IF, FC, IHC, WB.
See all EPN2 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Rat, Monkey
Clone
CBFYE-1054
Antibody Isotype
IgG1
Application
IF, FC, IHC, WB

Basic Information

Immunogen
EPN2 antibody was raised in Mouse using full length human recombinant protein of human EPN2 produced in HEK293T cell as the immunogen
Specificity
Human, Rat, Monkey
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.3, 1%BSA, 50% glycerol
Preservative
0.02% Sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Epsin 2
Introduction
This gene encodes a protein which interacts with clathrin and adaptor-related protein complex 2, alpha 1 subunit. The protein is found in a brain-derived clathrin-coated vesicle fraction and localizes to the peri-Golgi region and the cell periphery. The protein is thought to be involved in clathrin-mediated endocytosis. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.
Entrez Gene ID
Human22905
Monkey702600
Rat60443
UniProt ID
Alternative Names
Epsin 2; EPS-15-Interacting Protein 2; Eps15 Binding Protein; KIAA1065; Epsin-2; EHB21
Research Area
Plays a role in the formation of clathrin-coated invaginations and endocytosis.
Biological Process
Endocytosis Source: GO_Central
Negative regulation of sprouting angiogenesis Source: BHF-UCL
Negative regulation of vascular endothelial growth factor receptor signaling pathway Source: BHF-UCL
Positive regulation of Notch signaling pathway Source: BHF-UCL
Cellular Location
Cytoplasm; Clathrin-coated vesicle. In punctate structures throughout the cell, associated with clathrin-coated vesicles, and particularly concentrated in the region of the Golgi complex.
PTM
Ubiquitinated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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