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Mouse Anti-ETV3 Recombinant Antibody (ETV3F4D10) (CBMAB-E1969-FY)

This product is mouse antibody that recognizes ETV3. The antibody ETV3F4D10 can be used for immunoassay techniques such as: DB, ICC, WB.
See all ETV3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
ETV3F4D10
Antibody Isotype
IgG1
Application
DB, ICC, WB

Basic Information

Immunogen
ETV3 antibody was raised in mouse using recombinant Ets Variant Gene 3
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4, 1% BSA
Preservative
0.05% Sodium azide
Concentration
0.1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
ets variant 3
Introduction
ETV3 (ETS Variant 3) is a Protein Coding gene. Diseases associated with ETV3 include Subclavian Steal Syndrome. Among its related pathways are Macrophage Differentiation and Growth Inhibition by METS. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and RNA polymerase II transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ERF.
Entrez Gene ID
2117
UniProt ID
P41162
Alternative Names
ETS Variant 3; Ets Variant Gene 3, ETS Family Transcriptional Repressor; Mitogenic Ets Transcriptional Suppressor; ETS Domain Transcriptional Repressor PE1; PE-1; METS; PE1; ETS Translocation Variant 3
Research Area
Transcriptional repressor that contribute to growth arrest during terminal macrophage differentiation by repressing target genes involved in Ras-dependent proliferation. Represses MMP1 promoter activity.
Biological Process
Cell differentiation Source: GO_Central
Cellular response to granulocyte macrophage colony-stimulating factor stimulus Source: Ensembl
Negative regulation of cell population proliferation Source: Ensembl
Regulation of transcription by RNA polymerase II Source: GO_Central
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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