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Mouse Anti-FABP3 Recombinant Antibody (CBYY-C2456) (CBMAB-C3896-YY)

This product is mouse antibody that recognizes FABP3. The antibody CBYY-C2456 can be used for immunoassay techniques such as: WB, IP, IHC-P, IHC-Fr
See all FABP3 antibodies

Summary

Host Animal
Mouse
Specificity
Mouse, Rat, Human
Clone
CBYY-C2456
Antibody Isotype
IgG1
Application
WB, IP, IHC-P, IHC-Fr

Basic Information

Specificity
Mouse, Rat, Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Protein G purified
Buffer
0.1 mg/mL
Concentration
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Fatty Acid Binding Protein 3
Entrez Gene ID
Human2170
Mouse14077
Rat79131
UniProt ID
HumanP05413
MouseP11404
RatP07483
Alternative Names
Fc Fragment Of IgG Receptor IIa; Fc Fragment Of IgG, Low Affinity IIa, Receptor (CD32); Immunoglobulin G Fc Receptor II; IgG Fc Receptor II-A; Fc-Gamma-RIIa; FcRII-A; FCGR2A1; CDw32; IGFR2; FCG2;
Research Area
FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters.
Biological Process
Brown fat cell differentiation Source: Ensembl
Cholesterol homeostasis Source: BHF-UCL
Fatty acid metabolic process Source: Ensembl
Intracellular lipid transport Source: BHF-UCL
Long-chain fatty acid transport Source: ARUK-UCL
Negative regulation of cell population proliferation Source: ProtInc
Phospholipid homeostasis Source: BHF-UCL
Positive regulation of long-chain fatty acid import into cell Source: ARUK-UCL
Positive regulation of phospholipid biosynthetic process Source: BHF-UCL
Regulation of fatty acid oxidation Source: BHF-UCL
Regulation of phosphatidylcholine biosynthetic process Source: Ensembl
Response to drug Source: Ensembl
Response to fatty acid Source: Ensembl
Response to insulin Source: Ensembl
Cellular Location
Cytoplasm

Dogra, A., Kour, D., Gour, A., Bhardwaj, M., Bag, S., Dhiman, S. K., ... & Nandi, U. (2022). Ameliorating effect of rutin against diclofenac-induced cardiac injury in rats with underlying function of FABP3, MYL3, and ANP. Drug and Chemical Toxicology, 1-12.

Liu, Z. Z., Hong, C. G., Hu, W. B., Chen, M. L., Duan, R., Li, H. M., ... & Xie, H. (2021). Autophagy receptor OPTN (optineurin) regulates mesenchymal stem cell fate and bone-fat balance during aging by clearing FABP3. Autophagy, 17(10), 2766-2782.

Matsuo, K., Kawahata, I., Melki, R., Bousset, L., Owada, Y., & Fukunaga, K. (2021). Suppression of α-synuclein propagation after intrastriatal injection in FABP3 null mice. Brain research, 1760, 147383.

Lee, S. M., Lee, S. H., Jung, Y., Lee, Y., Yoon, J. H., Choi, J. Y., ... & Kwon, K. S. (2020). FABP3-mediated membrane lipid saturation alters fluidity and induces ER stress in skeletal muscle with aging. Nature communications, 11(1), 1-15.

Ayo, A., Figueras, E., Schachtsiek, T., Budak, M., Sewald, N., & Laakkonen, P. (2020). Tumor-Targeting Peptides: The Functional Screen of Glioblastoma Homing Peptides to the Target Protein FABP3 (MDGI). Cancers, 12(7), 1836.

Bi, Y., Yuan, X., Zhu, P., Chen, Y., Chen, G., & Chang, G. (2020). A novel long noncoding RNA, ENSGALG00000021686, regulates the intracellular transport of fatty acids by targeting the FABP3 gene in chicken. Biochemical and Biophysical Research Communications, 528(4), 706-712.

Cheng, A., Shinoda, Y., Yamamoto, T., Miyachi, H., & Fukunaga, K. (2019). Development of FABP3 ligands that inhibit arachidonic acid-induced α-synuclein oligomerization. Brain research, 1707, 190-197.

Yamamoto, Y., Kida, H., Kagawa, Y., Yasumoto, Y., Miyazaki, H., Islam, A., ... & Owada, Y. (2018). FABP3 in the anterior cingulate cortex modulates the methylation status of the glutamic acid decarboxylase67 promoter region. Journal of Neuroscience, 38(49), 10411-10423.

Sepe, F. N., Chiasserini, D., & Parnetti, L. (2018). Role of FABP3 as biomarker in Alzheimer's disease and synucleinopathies. Future Neurology, 13(4), 199-207.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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