FABP3
The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is a candidate tumor suppressor gene for human breast cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
Full Name
Fatty Acid Binding Protein 3
Research Area
FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters.
Biological Process
Brown fat cell differentiation Source: Ensembl
Cholesterol homeostasis Source: BHF-UCL
Fatty acid metabolic process Source: Ensembl
Intracellular lipid transport Source: BHF-UCL
Long-chain fatty acid transport Source: ARUK-UCL
Negative regulation of cell population proliferation Source: ProtInc
Phospholipid homeostasis Source: BHF-UCL
Positive regulation of long-chain fatty acid import into cell Source: ARUK-UCL
Positive regulation of phospholipid biosynthetic process Source: BHF-UCL
Regulation of fatty acid oxidation Source: BHF-UCL
Regulation of phosphatidylcholine biosynthetic process Source: Ensembl
Response to drug Source: Ensembl
Response to fatty acid Source: Ensembl
Response to insulin Source: Ensembl
Cholesterol homeostasis Source: BHF-UCL
Fatty acid metabolic process Source: Ensembl
Intracellular lipid transport Source: BHF-UCL
Long-chain fatty acid transport Source: ARUK-UCL
Negative regulation of cell population proliferation Source: ProtInc
Phospholipid homeostasis Source: BHF-UCL
Positive regulation of long-chain fatty acid import into cell Source: ARUK-UCL
Positive regulation of phospholipid biosynthetic process Source: BHF-UCL
Regulation of fatty acid oxidation Source: BHF-UCL
Regulation of phosphatidylcholine biosynthetic process Source: Ensembl
Response to drug Source: Ensembl
Response to fatty acid Source: Ensembl
Response to insulin Source: Ensembl
Cellular Location
Cytoplasm
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Anti-FABP3 antibodies
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Target: FABP3
Host: Rat
Antibody Isotype: IgG2a
Specificity: Human, Mouse, Rat
Clone: CBXF-2299
Application*: WB, IH
Target: FABP3
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXF-2801
Application*: IH
Target: FABP3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXF-0244
Application*: IH
Target: FABP3
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBXF-0241
Application*: E, WB
Target: FABP3
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXF-1372
Application*: E, WB
Target: FABP3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: CBXF-2195
Application*: WB, IP, IF, E
Target: FABP3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: CBXF-3331
Application*: WB, IP, IF, E, P
Target: FABP3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: CBXF-2797
Application*: WB, IP, IF, E
Target: FABP3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: CBXF-0238
Application*: E, WB, IP
Target: FABP3
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Mouse, Rat
Clone: CBXF-0235
Application*: WB, IP
Target: FABP3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-0232
Application*: E, WB
Target: FABP3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYH-3416
Application*: IH, WB
Target: FABP3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-3415
Application*: E
Target: FABP3
Expressed Host: E. coli
Sequence: Amino Acid: 1-133
Target: FABP3
Expressed Host: E. coli
Sequence: Amino Acid: 1-133
Target: FABP3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse, Rat
Clone: CBXF-1224
Application*: P, WB
Target: FABP3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-0233
Application*: E
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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