Mouse Recombinant FABP3 protein (V2LY-0526-LY8285)

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Basic Information

Expressed Host
E. coli
Protein Species
Mouse
Protein Construction
This product is Mouse Recombinant FABP3 protein consist of Amino Acid: 1-133 and predicts a molecular mass of 14.8 kDa.
Molecule Mass
14.8 kDa
Sequence
Amino Acid: 1-133
Species
Mouse

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity
>95% as determined by SDS-PAGE.
Endotoxin
Please contact us for more information.
Format
Lyophilized
Reconstitution
Allow the vial and reconstitution buffer to equilibrate to room temperature. Briefly centrifuge or tap down the vial to ensure that all lyophilized powder is collected at the bottom of the vial. For the reconstitution of this product, we recommend adding PBS or sterile water to achieve a final antibody concentration of 1 mg/mL. Allow the vial to reconstitute for 10-15 minutes at room temperature with gentle agitation. Avoid vigorous shaking that can cause foaming and antibody denaturation. Aliquot into volumes based on your experiment and store liquid protein at -20°C or -80°C for long time.
Buffer
Lyophilized from sterile PBS
Preservative
None
Storage
Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
More Infomation

Target

Full Name
Fatty Acid Binding Protein 3
Research Area
FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters.
Biological Process
Brown fat cell differentiation Source: Ensembl
Cholesterol homeostasis Source: BHF-UCL
Fatty acid metabolic process Source: Ensembl
Intracellular lipid transport Source: BHF-UCL
Long-chain fatty acid transport Source: ARUK-UCL
Negative regulation of cell population proliferation Source: ProtInc
Phospholipid homeostasis Source: BHF-UCL
Positive regulation of long-chain fatty acid import into cell Source: ARUK-UCL
Positive regulation of phospholipid biosynthetic process Source: BHF-UCL
Regulation of fatty acid oxidation Source: BHF-UCL
Regulation of phosphatidylcholine biosynthetic process Source: Ensembl
Response to drug Source: Ensembl
Response to fatty acid Source: Ensembl
Response to insulin Source: Ensembl
Cellular Location
Cytoplasm

Dogra, A., Kour, D., Gour, A., Bhardwaj, M., Bag, S., Dhiman, S. K., ... & Nandi, U. (2022). Ameliorating effect of rutin against diclofenac-induced cardiac injury in rats with underlying function of FABP3, MYL3, and ANP. Drug and Chemical Toxicology, 1-12.

Liu, Z. Z., Hong, C. G., Hu, W. B., Chen, M. L., Duan, R., Li, H. M., ... & Xie, H. (2021). Autophagy receptor OPTN (optineurin) regulates mesenchymal stem cell fate and bone-fat balance during aging by clearing FABP3. Autophagy, 17(10), 2766-2782.

Matsuo, K., Kawahata, I., Melki, R., Bousset, L., Owada, Y., & Fukunaga, K. (2021). Suppression of α-synuclein propagation after intrastriatal injection in FABP3 null mice. Brain research, 1760, 147383.

Lee, S. M., Lee, S. H., Jung, Y., Lee, Y., Yoon, J. H., Choi, J. Y., ... & Kwon, K. S. (2020). FABP3-mediated membrane lipid saturation alters fluidity and induces ER stress in skeletal muscle with aging. Nature communications, 11(1), 1-15.

Ayo, A., Figueras, E., Schachtsiek, T., Budak, M., Sewald, N., & Laakkonen, P. (2020). Tumor-Targeting Peptides: The Functional Screen of Glioblastoma Homing Peptides to the Target Protein FABP3 (MDGI). Cancers, 12(7), 1836.

Bi, Y., Yuan, X., Zhu, P., Chen, Y., Chen, G., & Chang, G. (2020). A novel long noncoding RNA, ENSGALG00000021686, regulates the intracellular transport of fatty acids by targeting the FABP3 gene in chicken. Biochemical and Biophysical Research Communications, 528(4), 706-712.

Cheng, A., Shinoda, Y., Yamamoto, T., Miyachi, H., & Fukunaga, K. (2019). Development of FABP3 ligands that inhibit arachidonic acid-induced α-synuclein oligomerization. Brain research, 1707, 190-197.

Yamamoto, Y., Kida, H., Kagawa, Y., Yasumoto, Y., Miyazaki, H., Islam, A., ... & Owada, Y. (2018). FABP3 in the anterior cingulate cortex modulates the methylation status of the glutamic acid decarboxylase67 promoter region. Journal of Neuroscience, 38(49), 10411-10423.

Sepe, F. N., Chiasserini, D., & Parnetti, L. (2018). Role of FABP3 as biomarker in Alzheimer's disease and synucleinopathies. Future Neurology, 13(4), 199-207.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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