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Mouse Anti-FBXO27 Recombinant Antibody (1G6) (CBMAB-A2884-LY)

The product is antibody recognizes FBXO27. The antibody 1G6 immunoassay techniques such as: sELISA, ELISA.
See all FBXO27 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1G6
Antibody Isotype
IgG2a, κ
Application
sELISA, ELISA

Basic Information

Immunogen
FBXO27 (NP_849142, 192 a.a. ~ 283 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
F-box protein 27
Introduction
Members of the F-box protein family, such as FBXO27, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM
Entrez Gene ID
126433
UniProt ID
Q8NI29
Alternative Names
FBG5; Fbx27
Research Area
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Able to recognize and bind denatured glycoproteins, which are modified with complex-type oligosaccharides.
Biological Process
Glycoprotein catabolic process Source: GO_Central
Protein ubiquitination Source: GOC
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process Source: GO_Central
Ubiquitin-dependent ERAD pathway Source: GO_Central
Cellular Location
Cytosol; Cytoplasm; SCF ubiquitin ligase complex
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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