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Rabbit Anti-FGD3 Recombinant Antibody (CBXF-1100) (CBMAB-F0855-CQ)

This product is a rabbit antibody that recognizes FGD3. The antibody CBXF-1100 can be used for immunoassay techniques such as: WB, FC, IF.
See all FGD3 antibodies

Summary

Host Animal
Rabbit
Specificity
Human, Mouse, Rat
Clone
CBXF-1100
Antibody Isotype
IgG
Application
WB, FC, IF

Basic Information

Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
FYVE, RhoGEF And PH Domain Containing 3
Introduction
FGD3 (FYVE, RhoGEF And PH Domain Containing 3) is a Protein Coding gene. Diseases associated with FGD3 include Aarskog-Scott Syndrome. Among its related pathways are p75 NTR receptor-mediated signalling and Actin Nucleation by ARP-WASP Complex. Gene Ontology (GO) annotations related to this gene include guanyl-nucleotide exchange factor activity and small GTPase binding. An important paralog of this gene is FGD1.
Entrez Gene ID
Human89846
Mouse30938
Rat361223
UniProt ID
HumanQ5JSP0
MouseO88842
RatD3ZS34
Alternative Names
FYVE, RhoGEF And PH Domain Containing 3; Zinc Finger FYVE Domain-Containing Protein 5; FGD1 Family, Member 3; ZFYVE5; FYVE, RhoGEF And PH Domain-Containing Protein 3; Faciogenital Dysplasia 3;
Research Area
Promotes the formation of filopodia. May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape (By similarity).
Biological Process
Actin cytoskeleton organization Source: UniProtKB
Cytoskeleton organization Source: UniProtKB
Filopodium assembly Source: UniProtKB
Regulation of cell shape Source: UniProtKB
Regulation of GTPase activity Source: UniProtKB
Regulation of small GTPase mediated signal transduction Source: Reactome
Cellular Location
Cytoplasm; Cytoskeleton
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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