FGD3

FGD3 (FYVE, RhoGEF And PH Domain Containing 3) is a Protein Coding gene. Diseases associated with FGD3 include Aarskog-Scott Syndrome. Among its related pathways are p75 NTR receptor-mediated signalling and Actin Nucleation by ARP-WASP Complex. Gene Ontology (GO) annotations related to this gene include guanyl-nucleotide exchange factor activity and small GTPase binding. An important paralog of this gene is FGD1.
Full Name
FYVE, RhoGEF And PH Domain Containing 3
Research Area
Promotes the formation of filopodia. May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape (By similarity).
Biological Process
Actin cytoskeleton organization Source: UniProtKB
Cytoskeleton organization Source: UniProtKB
Filopodium assembly Source: UniProtKB
Regulation of cell shape Source: UniProtKB
Regulation of GTPase activity Source: UniProtKB
Regulation of small GTPase mediated signal transduction Source: Reactome
Cellular Location
Cytoplasm; Cytoskeleton
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Anti-FGD3 antibodies

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Mouse Anti-FGD3 Recombinant Antibody (CBXF-2968) (V2LY-0925-LY1396)

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Target: FGD3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: CBXF-2968
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-FGD3 Recombinant Antibody (CBXF-1100) (V2LY-0925-LY1395)

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Target: FGD3
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat
Clone: CBXF-1100
Application*: WB, IP, IF, E
Datasheet SDS

FGD3 Matched Antibody Pair (428) (APMAB-428LY)

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Target: FGD3
Specificity: Human
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FGD3 Matched Antibody Pair (427) (APMAB-427LY)

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Target: FGD3
Specificity: Human
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FGD3 Matched Antibody Pair (426) (APMAB-426LY)

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Target: FGD3
Specificity: Human
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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