Mouse Anti-FGD3 Recombinant Antibody (CBXF-2968) (V2LY-0925-LY1396)

Name: Mouse Anti-FGD3 Recombinant Antibody (CBXF-2968)
SKU: V2LY-0925-LY1396
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBXF-2968

Application

WB, IP, IF, ELISA

Immunogen

Amino acids 73-173 mapping near the N-terminus of human FGD3.

Host Species

Mouse

Specificity

Human, Mouse, Rat

Antibody Isotype

IgG1, κ

Clonality

Monoclonal

Application Notes

Application	Note
ELISA	1:100-1:1,000
WB	1:100-1:1,000
IP	1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)
IF(ICC)	1:50-1:500

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

Gelatin & PBS

Preservative

Sodium azide

Concentration

0.2 mg/ml

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

FYVE, RhoGEF And PH Domain Containing 3

Entrez Gene ID

Human	89846
Mouse	30938
Rat	361223

UniProt ID

Human	Q5JSP0
Mouse	O88842
Rat	D3ZS34

Research Area

Promotes the formation of filopodia. May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape (By similarity).

Biological Process

Actin cytoskeleton organization Source: UniProtKB
Cytoskeleton organization Source: UniProtKB
Filopodium assembly Source: UniProtKB
Regulation of cell shape Source: UniProtKB
Regulation of GTPase activity Source: UniProtKB
Regulation of small GTPase mediated signal transduction Source: Reactome

Cellular Location

Cytoplasm; Cytoskeleton

Guo, F., Cheng, X., Jing, B., Wu, H., & Jin, X. (2022). FGD3 binds with HSF4 to suppress p65 expression and inhibit pancreatic cancer progression. Oncogene, 41(6), 838-851.

Susini, T., & Renda, I. (2020). FGD3 gene as a new prognostic factor in breast cancer. Anticancer Research, 40(7), 3645-3649.

Renda, I., Bianchi, S., Vezzosi, V., Nori, J., Vanzi, E., Tavella, K., & Susini, T. (2019). Expression of FGD3 gene as prognostic factor in young breast cancer patients. Scientific reports, 9(1), 1-8.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Antibody Pairs

FGD3 Matched Antibody Pair (426) (CAT#: APMAB-426LY)

FGD3 Matched Antibody Pair (427) (CAT#: APMAB-427LY)

FGD3 Matched Antibody Pair (428) (CAT#: APMAB-428LY)

Related Products

Mouse Anti-FGD3 Recombinant Antibody (CBXF-1100) (CAT#: V2LY-0925-LY1395)

FGD3 Matched Antibody Pair (426) (CAT#: APMAB-426LY)

FGD3 Matched Antibody Pair (427) (CAT#: APMAB-427LY)

FGD3 Matched Antibody Pair (428) (CAT#: APMAB-428LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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