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Mouse Anti-FMN1 Recombinant Antibody (CBXF-1757) (CBMAB-F3292-CQ)

This product is a mouse antibody that recognizes FMN1. The antibody CBXF-1757 can be used for immunoassay techniques such as: WB, IP, IF, ELISA.
See all FMN1 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
CBXF-1757
Antibody Isotype
IgG
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
formin 1
Introduction
This gene belongs to the formin homology family and encodes a protein that has a role in the formation of adherens junction and the polymerization of linear actin cables. The homologous gene in mouse is associated with limb deformity. Alternatively spliced transcript variants have been found for this gene.
Entrez Gene ID
Human342184
Mouse14260
Rat296512
UniProt ID
HumanQ68DA7
MouseQ05860
RatD4A4Y9
Alternative Names
Formin 1; Limb Deformity Protein Homolog; Formin (Limb Deformity); FMN; LD; Limb Deformity Protein; Formin-1;
Function
Plays a role in the formation of adherens junction and the polymerization of linear actin cables.
Biological Process
Actin nucleation Source: InterPro
Forelimb morphogenesis Source: Ensembl
Gene expression Source: Ensembl
Hindlimb morphogenesis Source: Ensembl
Positive regulation of actin nucleation Source: Ensembl
Positive regulation of focal adhesion assembly Source: Ensembl
Skeletal system morphogenesis Source: Ensembl
Ureteric bud invasion Source: Ensembl
Cellular Location
Cell membrane; Cytoplasm; Nucleus; Adherens junction. Localization to the adherens junctions is alpha-catenin-dependent. Also localizes to F-actin bundles originating from adherens junctions and to microtubules (By similarity).
PTM
Phosphorylated on serine and possibly threonine residues.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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