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Rabbit Anti-GPR153 Recombinant Antibody (EG1385) (CBMAB-EN1664-LY)

The product is antibody recognizes GPR153. The antibody EG1385 immunoassay techniques such as: WB: 1:500~1:1000 IF: 1:100~1:500 ELISA: 1:1000.
See all GPR153 antibodies

Summary

Host Animal
Rabbit
Specificity
Human, Mouse
Clone
EG1385
Antibody Isotype
IgG
Application
WB: 1:500~1:1000 IF: 1:100~1:500 ELISA: 1:1000

Basic Information

Immunogen
The antibody was produced against synthesized peptide derived from internal of human GPR153.
Specificity
Human, Mouse
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
G protein-coupled receptor 153
Introduction
This gene encodes an integral membrane protein that belongs to the Class A rhodopsin superfamily of G protein coupled receptors. The encoded protein is expressed primarily in the central nervous system. A knockdown of the orthologous gene in rat is associated with a significant reduction in food intake and impaired decision making ability. Mutations in this gene are associated with schizophrenia, autism, and other neuropsychiatric disorders. The expression of this gene is activated by the glioma-associated oncogene homolog 1 transcription factor which, in turn, is activated by sonic hedgehog in normal and tumorigenic cells.
Entrez Gene ID
Human387509
Mouse100129
UniProt ID
HumanQ6NV75
MouseQ8K0Z9
Alternative Names
PGR1
Function
Orphan receptor.
Cellular Location
Cell membrane
Topology
Extracellular: 1-11
Helical: 12-32
Cytoplasmic: 33-41
Helical: 42-62
Extracellular: 63-84
Helical: 85-105
Cytoplasmic: 106-126
Helical: 127-147
Extracellular: 148-175
Helical: 176-196
Cytoplasmic: 197-243
Helical: 244-264
Extracellular: 265-276
Helical: 277-297
Cytoplasmic: 298-609
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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